Endothelial Growth Factors
"Endothelial Growth Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.
| Descriptor ID |
D016228
|
| MeSH Number(s) |
D12.644.276.390 D12.776.467.390 D23.529.390
|
| Concept/Terms |
Endothelial Growth Factors- Endothelial Growth Factors
- Growth Factors, Endothelial
- Endo-GF
- Endothelial Growth Factor Polypeptides
- Endothelial Growth Factor
- Growth Factor, Endothelial
- ECDGF
- Endothelial Cell-Derived Growth Factors
- Endothelial Cell Derived Growth Factors
|
Below are MeSH descriptors whose meaning is more general than "Endothelial Growth Factors".
Below are MeSH descriptors whose meaning is more specific than "Endothelial Growth Factors".
This graph shows the total number of publications written about "Endothelial Growth Factors" by people in this website by year, and whether "Endothelial Growth Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 1 | 3 |
| 1999 | 5 | 3 | 8 |
| 2000 | 2 | 3 | 5 |
| 2001 | 2 | 5 | 7 |
| 2002 | 2 | 4 | 6 |
| 2003 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Endothelial Growth Factors" by people in Profiles.
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Safety of recent ophthalmic drugs and devices for wet macular degeneration. Curr Opin Ophthalmol. 2023 Sep 01; 34(5):363-368.
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Age differential response to bevacizumab therapy in choroidal neovascularization in rabbits. Exp Eye Res. 2022 10; 223:109215.
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Adding a humanized antibody to vascular endothelial growth factor (Bevacizumab, Avastin) to chemotherapy improves survival in metastatic colorectal cancer. Clin Colorectal Cancer. 2003 Aug; 3(2):85-8.
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Expression patterns of vascular endothelial growth factor in human cardiac allografts: association with rejection. Transplantation. 2003 Jul 15; 76(1):224-30.
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Clinical relevance of VEGF receptors 1 and 2 in patients with chronic myelogenous leukemia. Leuk Res. 2003 Jul; 27(7):661-9.
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Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene. Cancer Res. 2003 May 15; 63(10):2675-80.
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Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene. 2003 Jan 23; 22(3):319-29.
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Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J Biol Chem. 2003 Apr 11; 278(15):12605-8.
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Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes. Kidney Int. 2002 Sep; 62(3):901-13.
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A novel peptide isolated from a phage display library inhibits tumor growth and metastasis by blocking the binding of vascular endothelial growth factor to its kinase domain receptor. J Biol Chem. 2002 Nov 08; 277(45):43137-42.