"Ephrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signaling proteins that are ligands for the EPH FAMILY RECEPTORS. They are membrane-bound proteins that are attached to the CELL MEMBRANE either through a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR or through a transmembrane domain. Many of the ephrins are considered important intercellular signaling molecules that control morphogenic changes during embryogenesis.
| Descriptor ID |
D036342
|
| MeSH Number(s) |
D12.644.276.500 D12.776.467.500 D12.776.543.287 D23.529.500
|
| Concept/Terms |
Ephrins- Ephrins
- Eph Receptor Ligands
- Ligands, Eph Receptor
- Receptor Ligands, Eph
|
Below are MeSH descriptors whose meaning is more general than "Ephrins".
Below are MeSH descriptors whose meaning is more specific than "Ephrins".
This graph shows the total number of publications written about "Ephrins" by people in this website by year, and whether "Ephrins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ephrins" by people in Profiles.
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Molecular Network Analyses Implicate Death-Associated Protein Kinase 3 (DAPK3) as a Key Factor in Colitis-Associated Dysplasia Progression. Inflamm Bowel Dis. 2022 10 03; 28(10):1485-1496.
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Targeting Forward and Reverse EphB4/EFNB2 Signaling by a Peptide with Dual Functions. Sci Rep. 2020 01 16; 10(1):520.
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Evidence that the EphA2 receptor exacerbates ischemic brain injury. PLoS One. 2013; 8(1):e53528.
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EphB2 receptor forward signaling controls cortical growth cone collapse via Nck and Pak. Mol Cell Neurosci. 2013 Jan; 52:106-16.
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Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion. Mol Cancer Ther. 2012 Sep; 11(9):2021-32.
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Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia. Blood. 2010 Mar 25; 115(12):2412-9.
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Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology. 2006 Jul; 27(4):547-57.
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Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis. Microsc Res Tech. 2002 Oct 01; 59(1):58-67.