"Amphiregulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a membrane-bound protein that can be cleaved to release an active secreted form.
| Descriptor ID |
D066258
|
| MeSH Number(s) |
D12.644.276.382.249 D12.776.467.382.249 D12.776.543.029 D23.529.382.249
|
| Concept/Terms |
Amphiregulin- Amphiregulin
- Schwannoma-derived Growth Factor
- Schwannoma derived Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Amphiregulin".
Below are MeSH descriptors whose meaning is more specific than "Amphiregulin".
This graph shows the total number of publications written about "Amphiregulin" by people in this website by year, and whether "Amphiregulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2006 | 0 | 4 | 4 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 3 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Amphiregulin" by people in Profiles.
-
Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 11 16; 11(1):5799.
-
The endogenous hydrogen sulfide generating system regulates ovulation. Free Radic Biol Med. 2019 07; 138:43-52.
-
Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802. Blood Adv. 2018 08 14; 2(15):1882-1888.
-
Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity. J Immunol. 2018 02 01; 200(3):909-914.
-
Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer. Br J Cancer. 2016 06 14; 114(12):1352-61.
-
Amphiregulin in Cancer: New Insights for Translational Medicine. Trends Cancer. 2016 03; 2(3):111-113.
-
An antibody to amphiregulin, an abundant growth factor in patients' fluids, inhibits ovarian tumors. Oncogene. 2016 Jan 28; 35(4):438-47.
-
Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer. Oncogene. 2014 May 29; 33(22):2846-56.
-
HER family receptor and ligand status in thymic carcinoma. Lung Cancer. 2012 Sep; 77(3):515-21.
-
LH-induced neuregulin 1 (NRG1) type III transcripts control granulosa cell differentiation and oocyte maturation. Mol Endocrinol. 2011 Jan; 25(1):104-16.