"Theca Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The flattened stroma cells forming a sheath or theca outside the basal lamina lining the mature OVARIAN FOLLICLE. Thecal interstitial or stromal cells are steroidogenic, and produce primarily ANDROGENS which serve as precusors of ESTROGENS in the GRANULOSA CELLS.
| Descriptor ID |
D013799
|
| MeSH Number(s) |
A05.360.319.114.630.535.400 A06.407.312.497.535.600 A11.329.850
|
| Concept/Terms |
Theca Cells- Theca Cells
- Cell, Theca
- Cells, Theca
- Theca Cell
- Ovarian Interstitial Cells
- Cell, Ovarian Interstitial
- Cells, Ovarian Interstitial
- Interstitial Cell, Ovarian
- Interstitial Cells, Ovarian
- Ovarian Interstitial Cell
|
Below are MeSH descriptors whose meaning is more general than "Theca Cells".
Below are MeSH descriptors whose meaning is more specific than "Theca Cells".
This graph shows the total number of publications written about "Theca Cells" by people in this website by year, and whether "Theca Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 3 | 0 | 3 |
| 2015 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Theca Cells" by people in Profiles.
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Targeted deletion of NR2F2 and VCAM1 in theca cells impacts ovarian follicular development: insights into polycystic ovary syndrome??. Biol Reprod. 2024 Apr 11; 110(4):782-797.
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VCAM1 Is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess. Endocrinology. 2019 06 01; 160(6):1377-1393.
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Ovarian Follicular Theca Cell Recruitment, Differentiation, and Impact on Fertility: 2017 Update. Endocr Rev. 2018 02 01; 39(1):1-20.
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Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice. Mol Cell Endocrinol. 2017 03 15; 444:26-37.
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Conditional Deletion of Bmal1 in Ovarian Theca Cells Disrupts Ovulation in Female Mice. Endocrinology. 2016 Feb; 157(2):913-27.
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Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells. Nat Commun. 2015 Apr 28; 6:6934.
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Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway. Mol Cell Endocrinol. 2013 Feb 05; 366(1):81-9.
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Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells. Mol Endocrinol. 2012 Oct; 26(10):1732-42.
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Metformin: direct inhibition of rat ovarian theca-interstitial cell proliferation. Fertil Steril. 2012 Jul; 98(1):207-14.
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Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway. Mol Endocrinol. 2010 Sep; 24(9):1782-93.