"Betacellulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An EGF family member that plays an important role in regulating growth and differentiation of PANCREATIC BETA CELLS. Betacellulin has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR.
| Descriptor ID |
D066259
|
| MeSH Number(s) |
D12.644.276.382.374 D12.776.467.382.374 D23.529.382.374
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Betacellulin".
Below are MeSH descriptors whose meaning is more specific than "Betacellulin".
This graph shows the total number of publications written about "Betacellulin" by people in this website by year, and whether "Betacellulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Betacellulin" by people in Profiles.
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The endogenous hydrogen sulfide generating system regulates ovulation. Free Radic Biol Med. 2019 07; 138:43-52.
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Anti-TCR? mAb in Combination With Neurogenin3 Gene Therapy Reverses Established Overt Type 1 Diabetes in Female NOD Mice. Endocrinology. 2017 10 01; 158(10):3140-3151.
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Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice. Gene Ther. 2015 Nov; 22(11):876-82.
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Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer. J Vis Exp. 2012 Oct 10; (68).
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Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice. Endocrinology. 2009 Nov; 150(11):4863-73.
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Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev Cell. 2009 Mar; 16(3):358-73.
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Paracrine and autocrine regulation of epidermal growth factor-like factors in cumulus oocyte complexes and granulosa cells: key roles for prostaglandin synthase 2 and progesterone receptor. Mol Endocrinol. 2006 Jun; 20(6):1352-65.
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NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Nat Med. 2003 May; 9(5):596-603.
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Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl). Genomics. 1995 Jul 01; 28(1):116-8.