Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.

Descriptor ID	D011973
MeSH Number(s)	D12.776.543.750.710.450
Concept/Terms	Receptors, LDL Receptors, LDL LDL Receptors LDL Receptors, Lipoprotein Receptors, Lipoprotein LDL Lipoprotein LDL Receptors Low Density Lipoprotein Receptors Receptors, Lipoprotein, LDL Receptors, Low Density Lipoprotein LDL Receptor Receptor, LDL Low Density Lipoprotein Receptor

Below are MeSH descriptors whose meaning is more general than "Receptors, LDL".

Below are MeSH descriptors whose meaning is related to "Receptors, LDL".

Below are MeSH descriptors whose meaning is more specific than "Receptors, LDL".