"Angiotensinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively.
| Descriptor ID |
D000808
|
| MeSH Number(s) |
D12.644.456.073.070 D12.644.861.020 D12.776.811.070 D12.776.872.020
|
| Concept/Terms |
Angiotensinogen- Angiotensinogen
- Serpin A8
- Renin-Substrate
- Renin Substrate
- Hypertensinogen
- Proangiotensin
|
Below are MeSH descriptors whose meaning is more general than "Angiotensinogen".
Below are MeSH descriptors whose meaning is more specific than "Angiotensinogen".
This graph shows the total number of publications written about "Angiotensinogen" by people in this website by year, and whether "Angiotensinogen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Angiotensinogen" by people in Profiles.
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Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity. Genes (Basel). 2020 10 25; 11(11).
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Genetic association analysis in a clinically and histologically confirmed otosclerosis population confirms association with the TGFB1 gene but suggests an association of the RELN gene with a clinically indistinguishable otosclerosis-like phenotype. Otol Neurotol. 2014 Jul; 35(6):1058-64.
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Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate. Kidney Int. 2014 Nov; 86(5):1031-8.
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Association of elevated urinary concentration of renin-angiotensin system components and severe AKI. Clin J Am Soc Nephrol. 2013 Dec; 8(12):2043-52.
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Urinary angiotensinogen predicts adverse outcomes among acute kidney injury patients in the intensive care unit. Crit Care. 2013 Apr 15; 17(2):R69.
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Urinary angiotensinogen and risk of severe AKI. Clin J Am Soc Nephrol. 2013 Feb; 8(2):184-93.
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Angiotensinogen gene M235T and T174M polymorphisms and susceptibility of pre-eclampsia: a meta-analysis. Ann Hum Genet. 2012 Sep; 76(5):377-86.
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The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach. Metabolism. 2011 Aug; 60(8):1150-7.
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Variants in blood pressure genes and the risk of renal cell carcinoma. Carcinogenesis. 2010 Apr; 31(4):614-20.
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No evidence for association between the renin-angiotensin-aldosterone system and otosclerosis in a large Belgian-Dutch population. Otol Neurotol. 2009 Dec; 30(8):1079-83.