"Angiotensin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A decapeptide that is cleaved from precursor angiotensinogen by RENIN. Angiotensin I has limited biological activity. It is converted to angiotensin II, a potent vasoconstrictor, after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME.
| Descriptor ID |
D000803
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| MeSH Number(s) |
D06.472.699.094.075 D12.644.400.070.075 D12.644.456.073.021 D12.644.548.058.075 D12.776.631.650.070.075 D23.469.050.050.025
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Angiotensin I".
Below are MeSH descriptors whose meaning is more specific than "Angiotensin I".
This graph shows the total number of publications written about "Angiotensin I" by people in this website by year, and whether "Angiotensin I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Angiotensin I" by people in Profiles.
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Angiotensin 1-7 exerts antioxidant effects, suppresses Mammalian Target of Rapamycin (mTOR) signaling, and inhibits apoptosis in renal proximal tubular cells. Peptides. 2024 Feb; 172:171136.
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Angiotensin (1-7) protects against renal ischemia-reperfusion injury via regulating expression of NRF2 and microRNAs in Fisher 344 rats. Am J Physiol Renal Physiol. 2022 07 01; 323(1):F33-F47.
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Synergism between Angiotensin receptors ligands: Role of Angiotensin-(1-7) in modulating AT2 R agonist response on nitric oxide in kidney cells. Pharmacol Res Perspect. 2020 12; 8(6):e00667.
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Kidney dopamine D1-like receptors and angiotensin 1-7 interaction inhibits renal Na+ transporters. Am J Physiol Renal Physiol. 2019 10 01; 317(4):F949-F956.
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Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin II type 2 receptor/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury. J Renin Angiotensin Aldosterone Syst. 2016 Jul; 17(3).
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TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Sci Adv. 2016 04; 2(4):e1501290.
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The ACE2-angiotensin-(1-7)-Mas axis protects against pancreatic cell damage in cell culture. Pancreas. 2015 Mar; 44(2):266-72.
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Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice. Hypertension. 2014 Aug; 64(2):362-8.
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Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese Zucker rats. Kidney Int. 2013 Nov; 84(5):931-9.
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Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment. Radiat Res. 2012 Jul; 178(1):46-56.