"Mannosidases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoside hydrolases that catalyze the hydrolysis of alpha or beta linked MANNOSE.
| Descriptor ID |
D008361
|
| MeSH Number(s) |
D08.811.277.450.625
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mannosidases".
Below are MeSH descriptors whose meaning is more specific than "Mannosidases".
This graph shows the total number of publications written about "Mannosidases" by people in this website by year, and whether "Mannosidases" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mannosidases" by people in Profiles.
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The cytoplasmic tail of human mannosidase Man1b1 contributes to catalysis-independent quality control of misfolded alpha1-antitrypsin. Proc Natl Acad Sci U S A. 2020 10 06; 117(40):24825-24836.
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A Golgi-localized mannosidase (MAN1B1) plays a non-enzymatic gatekeeper role in protein biosynthetic quality control. J Biol Chem. 2014 Apr 25; 289(17):11844-11858.
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ERManI is a target of miR-125b and promotes transformation phenotypes in hepatocellular carcinoma (HCC). PLoS One. 2013; 8(8):e72829.
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Golgi-situated endoplasmic reticulum a-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with ?-COP. Mol Biol Cell. 2013 Apr; 24(8):1111-21.
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Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system. Mol Biol Cell. 2011 Aug 15; 22(16):2810-22.
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Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase I modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency. Hepatology. 2009 Jul; 50(1):275-81.
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The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I. J Cell Sci. 2009 Apr 01; 122(Pt 7):976-84.
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Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis. J Biol Chem. 2007 Feb 16; 282(7):4841-4849.
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Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8229-34.
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Cell biology. Protein degradation unlocked. Science. 2003 Feb 28; 299(5611):1330-1.