Trypsin Inhibitor, Kazal Pancreatic
"Trypsin Inhibitor, Kazal Pancreatic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premataure activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS.
| Descriptor ID |
D014359
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| MeSH Number(s) |
D12.644.822.750.500 D12.776.124.050.850 D12.776.645.688.500
|
| Concept/Terms |
Trypsin Inhibitor, Kazal Pancreatic- Trypsin Inhibitor, Kazal Pancreatic
- Serine Protease Inhibitor Kazal-Type 1
- Serine Protease Inhibitor Kazal Type 1
- Pancreatic Secretory Trypsin Inhibitor
- SPINK1
- Trypsin Inhibitor Kazal Pancreatic
- Pancreatic Trypsin Secretory Inhibitor, Kazal
- Inhibitor, Tumor-Associated Trypsin
- Inhibitor, Tumor Associated Trypsin
- Trypsin Inhibitor, Tumor-Associated
- Trypsin Inhibitor, Tumor Associated
- Tumor-Associated Trypsin Inhibitor
- Tumor Associated Trypsin Inhibitor
- Acidic Pancreatic Trypsin Inhibitor
- Pancreatic Secretory Trypsin Inhibitor, Kazal
- Serine Peptidase Inhibitor, Kazal-Type 1
- Serine Peptidase Inhibitor, Kazal Type 1
- Kazal Pancreatic Trypsin Inhibitor
|
Below are MeSH descriptors whose meaning is more general than "Trypsin Inhibitor, Kazal Pancreatic".
Below are MeSH descriptors whose meaning is more specific than "Trypsin Inhibitor, Kazal Pancreatic".
This graph shows the total number of publications written about "Trypsin Inhibitor, Kazal Pancreatic" by people in this website by year, and whether "Trypsin Inhibitor, Kazal Pancreatic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trypsin Inhibitor, Kazal Pancreatic" by people in Profiles.
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Pancreatic Enzyme Use Reduces Pancreatitis Frequency in Children With Acute Recurrent or Chronic Pancreatitis: A Report From INSPPIRE. Am J Gastroenterol. 2024 Oct 01; 119(10):2094-2102.
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Risk Factors Associated With Pediatric Acute Recurrent and Chronic Pancreatitis: Lessons From INSPPIRE. JAMA Pediatr. 2016 06 01; 170(6):562-9.
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Evaluation of ERG and SPINK1 by Immunohistochemical Staining and Clinicopathological Outcomes in a Multi-Institutional Radical Prostatectomy Cohort of 1067 Patients. PLoS One. 2015; 10(7):e0132343.
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Interactions and relationships of PTEN, ERG, SPINK1 and AR in castration-resistant prostate cancer. Histopathology. 2012 Mar; 60(4):645-52.
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Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer. BJU Int. 2009 May; 103(9):1256-69.
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Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder. Eur Urol. 2005 Sep; 48(3):424-31.
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Deoxyribonuclease I sensitivity of the ovomucoid-ovoinhibitor gene complex in oviduct nuclei and relative location of CR1 repetitive sequences. Biochemistry. 1987 Oct 20; 26(21):6831-40.