SAMEER JHAVAR

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Radiation Oncology
Address2401 S 31st St
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    1. Jensen GL, Pourfarrokh N, Volz M, Morales LL, Walker K, Hammonds KP, El-Ghamry M, Wong L, Hodjat P, Castro E, Rao A, Jhavar SG. Improved Pathologic response to chemoradiation in MGMT methylated locally advanced rectal cancer. Clin Transl Radiat Oncol. 2023 Sep; 42:100667. PMID: 37560324; PMCID: PMC10406619.
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    2. Swanson GP, Hammonds K, Jhavar S. Salvage prostate bed plus elective pelvic node radiation without androgen deprivation therapy. J Cancer Res Clin Oncol. 2023 Nov; 149(14):13231-13237. PMID: 37480525.
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    3. Elsaqa M, Slade A, Lingeman J, Piroozi A, Wagner K, Jhavar S, El Tayeb MM. Holmium Laser Enucleation of Prostate in Patients with Pre-Existing Localized Prostate Cancer, Dual Center Study. J Endourol. 2023 03; 37(3):330-334. PMID: 36463424.
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    4. Jensen GL, Jhavar SG, Ha CS, Hammonds KP, Swanson GP. The cost of elective nodal coverage in prostate cancer: Late quality of life outcomes and dosimetric analysis with 0, 45 or 54?Gy to the pelvis. Clin Transl Radiat Oncol. 2022 Sep; 36:63-69. PMID: 35813937; PMCID: PMC9256976.
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    5. Swanson GP, Hammonds K, Jhavar S. Reference Results for Blood Parameter Changes and Recovery after Pelvic Radiation without Chemotherapy. Hematol Rep. 2022 May 12; 14(2):155-164. PMID: 35645304; PMCID: PMC9149904.
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    6. Jensen GL, Naziri J, Hammonds KP, Jhavar SG, Swanson G. C-Reactive Protein Is a Poor Marker of Baseline Inflammation in Prostate Cancer and Response to Radiotherapy or Androgen Ablation. Cureus. 2021 Nov; 13(11):e19639. PMID: 34926085; PMCID: PMC8673689.
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    7. Bailey SM, Luxton JJ, McKenna MJ, Taylor LE, George KA, Jhavar SG, Swanson GP. Ad Astra - telomeres in space! Int J Radiat Biol. 2022; 98(3):395-403. PMID: 34270368.
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    8. Luxton JJ, McKenna MJ, Lewis AM, Taylor LE, Jhavar SG, Swanson GP, Bailey SM. Telomere Length Dynamics and Chromosomal Instability for Predicting Individual Radiosensitivity and Risk via Machine Learning. J Pers Med. 2021 Mar 08; 11(3). PMID: 33800260; PMCID: PMC8002073.
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    9. Jensen GL, Axelrud G, Fink D, Hammonds K, Walker K, Volz M, Gowan A, Rao A, Deb N, Jhavar SG. Improved local control in p16 negative oropharyngeal cancers with hypermethylated MGMT. Radiother Oncol. 2021 04; 157:234-240. PMID: 33577867.
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    10. Swanson GP, Jhavar SG, Hammonds K. The effect of pelvic radiation alone on lymphocyte subgroups. Clin Transl Radiat Oncol. 2020 Jul; 23:100-102. PMID: 32548314; PMCID: PMC7283969.
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    11. Jenkins DK, Swanson GP, Jhavar SG, Wagner KR, Ha CS, Chen W. The effect of radiation therapy on post-prostatectomy urinary function. Rep Pract Oncol Radiother. 2020 May-Jun; 25(3):442-446. PMID: 32405268; PMCID: PMC7210502.
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    12. Gestaut MM, Strober ED, Jhavar SG, Patel MK. To B(iopsy) or not to B(iopsy). J Cancer Res Ther. 2017 Oct-Dec; 13(6):1065-1067. PMID: 29237980.
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    13. Jhavar S, Swanson G, Pruszynski J. Risk factors for locoregional relapse after radical nephrectomy. Asia Pac J Clin Oncol. 2018 Jun; 14(3):192-197. PMID: 28488392.
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    14. Gestaut MM, Thawani N, Kim S, Gutti VR, Jhavar S, Deb N, Morrow A, Ward RA, Huang JH, Patel M. Single fraction spine stereotactic ablative body radiotherapy with volumetric modulated arc therapy. J Neurooncol. 2017 05; 133(1):165-172. PMID: 28409420.
      Citations: 1     Fields:    Translation:Humans
    15. Jhavar S, Pruszynski J, Gowan A, Boyle T, Deb N, Patel M. Intensity modulated radiation therapy after extra-pleural pneumonectomy for malignant pleural mesothelioma is feasible without fatal pulmonary toxicity and provides good survival. Asia Pac J Clin Oncol. 2018 Apr; 14(2):e88-e94. PMID: 28371288.
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    16. Jhavar S, Swanson G, Deb N, Littlejohn L, Pruszynski J, Machen G, Milburn P, Bird E. Durability of Artificial Urinary Sphincter With Prior Radiation Therapy. Clin Genitourin Cancer. 2017 04; 15(2):e175-e180. PMID: 27595559.
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    17. Snow AL, Xiao W, Stinson JR, Lu W, Chaigne-Delalande B, Zheng L, Pittaluga S, Matthews HF, Schmitz R, Jhavar S, Kuchen S, Kardava L, Wang W, Lamborn IT, Jing H, Raffeld M, Moir S, Fleisher TA, Staudt LM, Su HC, Lenardo MJ. Congenital B cell lymphocytosis explained by novel germline CARD11 mutations. J Exp Med. 2012 Nov 19; 209(12):2247-61. PMID: 23129749; PMCID: PMC3501355.
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    18. Schmitz R, Young RM, Ceribelli M, Jhavar S, Xiao W, Zhang M, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu X, Powell J, Yang Y, Xu W, Zhao H, Kohlhammer H, Rosenwald A, Kluin P, M?ller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Ogwang MD, Reynolds SJ, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pittaluga S, Wilson W, Waldmann TA, Rowe M, Mbulaiteye SM, Rickinson AB, Staudt LM. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature. 2012 Oct 04; 490(7418):116-20. PMID: 22885699; PMCID: PMC3609867.
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    19. Ngo VN, Young RM, Schmitz R, Jhavar S, Xiao W, Lim KH, Kohlhammer H, Xu W, Yang Y, Zhao H, Shaffer AL, Romesser P, Wright G, Powell J, Rosenwald A, Muller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Staudt LM. Oncogenically active MYD88 mutations in human lymphoma. Nature. 2011 Feb 03; 470(7332):115-9. PMID: 21179087; PMCID: PMC5024568.
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    20. Eeles R, Knee G, Jhavar S, Mangion J, Ebbs S, Gui G, Thomas S, Coppen M, A'hern R, Gray S, Cooper C, Bartek J, Yarnold J. Multicentric breast cancer: clonality and prognostic studies. Breast Cancer Res Treat. 2011 Oct; 129(3):703-16. PMID: 21080063.
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    21. McCarthy F, Dennis N, Flohr P, Jhavar S, Parker C, Cooper CS. High-density tissue microarrays from prostate needle biopsies. J Clin Pathol. 2011 Jan; 64(1):88-90. PMID: 21081515; PMCID: PMC3002837.
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    22. Whitaker HC, Kote-Jarai Z, Ross-Adams H, Warren AY, Burge J, George A, Bancroft E, Jhavar S, Leongamornlert D, Tymrakiewicz M, Saunders E, Page E, Mitra A, Mitchell G, Lindeman GJ, Evans DG, Blanco I, Mercer C, Rubinstein WS, Clowes V, Douglas F, Hodgson S, Walker L, Donaldson A, Izatt L, Dorkins H, Male A, Tucker K, Stapleton A, Lam J, Kirk J, Lilja H, Easton D, IMPACT Study Steering Committee, IMPACT Study Collaborators, UK GPCS Collaborators, Cooper C, Eeles R, Neal DE. The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine. PLoS One. 2010 Oct 13; 5(10):e13363. PMID: 20967219; PMCID: PMC2954177.
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    23. Edwards SM, Evans DG, Hope Q, Norman AR, Barbachano Y, Bullock S, Kote-Jarai Z, Meitz J, Falconer A, Osin P, Fisher C, Guy M, Jhavar SG, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Forrest MS, Dearnaley DP, Ardern-Jones AT, Page EC, Easton DF, Eeles RA, UK Genetic Prostate Cancer Study Collaborators and BAUS Section of Oncology. Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis. Br J Cancer. 2010 Sep 07; 103(6):918-24. PMID: 20736950; PMCID: PMC2948551.
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    24. Bancroft EK, Locke I, Ardern-Jones A, D'Mello L, McReynolds K, Lennard F, Barbachano Y, Barwell J, Walker L, Mitchell G, Dorkins H, Cummings C, Paterson J, Kote-Jarai Z, Mitra A, Jhavar S, Thomas S, Houlston R, Shanley S, Eeles RA. The carrier clinic: an evaluation of a novel clinic dedicated to the follow-up of BRCA1 and BRCA2 carriers--implications for oncogenetics practice. J Med Genet. 2010 Jul; 47(7):486-91. PMID: 20472659.
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    25. Al Olama AA, Kote-Jarai Z, Giles GG, Guy M, Morrison J, Severi G, Leongamornlert DA, Tymrakiewicz M, Jhavar S, Saunders E, Hopper JL, Southey MC, Muir KR, English DR, Dearnaley DP, Ardern-Jones AT, Hall AL, O'Brien LT, Wilkinson RA, Sawyer E, Lophatananon A, UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section o, UK Prostate testing for cancer and Treatment study (ProtecT Study) Collaborators, Horwich A, Huddart RA, Khoo VS, Parker CC, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Cooper C, Donovan JL, Hamdy FC, Neal DE, Eeles RA, Easton DF. Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat Genet. 2009 Oct; 41(10):1058-60. PMID: 19767752.
      Citations:    
    26. McCarthy F, Fletcher A, Dennis N, Cummings C, O'Donnell H, Clark J, Flohr P, Vergis R, Jhavar S, Parker C, Cooper CS. An improved method for constructing tissue microarrays from prostate needle biopsy specimens. J Clin Pathol. 2009 Aug; 62(8):694-8. PMID: 19638540; PMCID: PMC2709943.
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    27. Jackson AS, Reinsberg SA, Sohaib SA, Charles-Edwards EM, Jhavar S, Christmas TJ, Thompson AC, Bailey MJ, Corbishley CM, Fisher C, Leach MO, Dearnaley DP. Dynamic contrast-enhanced MRI for prostate cancer localization. Br J Radiol. 2009 Feb; 82(974):148-56. PMID: 19168692.
      Citations:    
    28. Guy M, Kote-Jarai Z, Giles GG, Al Olama AA, Jugurnauth SK, Mulholland S, Leongamornlert DA, Edwards SM, Morrison J, Field HI, Southey MC, Severi G, Donovan JL, Hamdy FC, Dearnaley DP, Muir KR, Smith C, Bagnato M, Ardern-Jones AT, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Cox A, Lewis S, Brown PM, Jhavar SG, Tymrakiewicz M, Lophatananon A, Bryant SL, UK Genetic Prostate Cancer Study Collaborators, British Association of Urological Surgeons' Section of Oncology, UK ProtecT Study Collaborators, Horwich A, Huddart RA, Khoo VS, Parker CC, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Fisher C, Jameson C, Cooper CS, English DR, Hopper JL, Neal DE, Easton DF, Eeles RA. Identification of new genetic risk factors for prostate cancer. Asian J Androl. 2009 Jan; 11(1):49-55. PMID: 19050691; PMCID: PMC3735221.
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    29. Jhavar S, Brewer D, Edwards S, Kote-Jarai Z, Attard G, Clark J, Flohr P, Christmas T, Thompson A, Parker M, Shepherd C, Stenman UH, Marchbank T, Playford RJ, Woodhouse C, Ogden C, Fisher C, Kovacs G, Corbishley C, Jameson C, Norman A, De-Bono J, Bjartell A, Eeles R, Cooper CS. Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer. BJU Int. 2009 May; 103(9):1256-69. PMID: 19040532.
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    30. Knight JF, Shepherd CJ, Rizzo S, Brewer D, Jhavar S, Dodson AR, Cooper CS, Eeles R, Falconer A, Kovacs G, Garrett MD, Norman AR, Shipley J, Hudson DL. TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer. Br J Cancer. 2008 Dec 02; 99(11):1849-58. PMID: 19002168; PMCID: PMC2600693.
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    31. Jhavar S, Bartlett J, Kovacs G, Corbishley C, Dearnaley D, Eeles R, Khoo V, Huddart R, Horwich A, Thompson A, Norman A, Brewer D, Cooper CS, Parker C. Biopsy tissue microarray study of Ki-67 expression in untreated, localized prostate cancer managed by active surveillance. Prostate Cancer Prostatic Dis. 2009; 12(2):143-7. PMID: 18762814.
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    32. Van As N, Charles-Edwards E, Jackson A, Jhavar S, Reinsberg S, Desouza N, Dearnaley D, Bailey M, Thompson A, Christmas T, Fisher C, Corbishley C, Sohaib S. Correlation of diffusion-weighted MRI with whole mount radical prostatectomy specimens. Br J Radiol. 2008 Jun; 81(966):456-62. PMID: 18487387.
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    33. Vergis R, Corbishley CM, Norman AR, Bartlett J, Jhavar S, Borre M, Heeboll S, Horwich A, Huddart R, Khoo V, Eeles R, Cooper C, Sydes M, Dearnaley D, Parker C. Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study. Lancet Oncol. 2008 Apr; 9(4):342-51. PMID: 18343725.
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    34. Eeles RA, Kote-Jarai Z, Giles GG, Olama AA, Guy M, Jugurnauth SK, Mulholland S, Leongamornlert DA, Edwards SM, Morrison J, Field HI, Southey MC, Severi G, Donovan JL, Hamdy FC, Dearnaley DP, Muir KR, Smith C, Bagnato M, Ardern-Jones AT, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Cox A, Lewis S, Brown PM, Jhavar SG, Tymrakiewicz M, Lophatananon A, Bryant SL, UK Genetic Prostate Cancer Study Collaborators, British Association of Urological Surgeons' Section of Oncology, UK ProtecT Study Collaborators, Horwich A, Huddart RA, Khoo VS, Parker CC, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Fisher C, Jamieson C, Cooper CS, English DR, Hopper JL, Neal DE, Easton DF. Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet. 2008 Mar; 40(3):316-21. PMID: 18264097.
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    35. Jhavar S, Reid A, Clark J, Kote-Jarai Z, Christmas T, Thompson A, Woodhouse C, Ogden C, Fisher C, Corbishley C, De-Bono J, Eeles R, Brewer D, Cooper C. Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays. J Mol Diagn. 2008 Jan; 10(1):50-7. PMID: 18165275; PMCID: PMC2175543.
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    36. Cooper CS, Campbell C, Jhavar S. Mechanisms of Disease: biomarkers and molecular targets from microarray gene expression studies in prostate cancer. Nat Clin Pract Urol. 2007 Dec; 4(12):677-87. PMID: 18059348.
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    37. Clark J, Attard G, Jhavar S, Flohr P, Reid A, De-Bono J, Eeles R, Scardino P, Cuzick J, Fisher G, Parker MD, Foster CS, Berney D, Kovacs G, Cooper CS. Complex patterns of ETS gene alteration arise during cancer development in the human prostate. Oncogene. 2008 Mar 27; 27(14):1993-2003. PMID: 17922029.
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    38. Clark J, Merson S, Jhavar S, Flohr P, Edwards S, Foster CS, Eeles R, Martin FL, Phillips DH, Crundwell M, Christmas T, Thompson A, Fisher C, Kovacs G, Cooper CS. Diversity of TMPRSS2-ERG fusion transcripts in the human prostate. Oncogene. 2007 Apr 19; 26(18):2667-73. PMID: 17043636.
      Citations:    
    39. Moule RN, Jhavar SG, Eeles RA. Genotype phenotype correlation in Li-Fraumeni syndrome kindreds and its implications for management. Fam Cancer. 2006; 5(2):129-33. PMID: 16736281.
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    40. Jhavar S, Corbishley CM, Dearnaley D, Fisher C, Falconer A, Parker C, Eeles R, Cooper CS. Construction of tissue microarrays from prostate needle biopsy specimens. Br J Cancer. 2005 Aug 22; 93(4):478-82. PMID: 16091762; PMCID: PMC2361582.
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    41. Jhavar SG, Fisher C, Jackson A, Reinsberg SA, Dennis N, Falconer A, Dearnaley D, Edwards SE, Edwards SM, Leach MO, Cummings C, Christmas T, Thompson A, Woodhouse C, Sandhu S, Cooper CS, Eeles RA. Processing of radical prostatectomy specimens for correlation of data from histopathological, molecular biological, and radiological studies: a new whole organ technique. J Clin Pathol. 2005 May; 58(5):504-8. PMID: 15858122; PMCID: PMC1770644.
      Citations:    
    42. Jhavar SG, Sarin R, Chopra S, Kotnis A, Mulherkar R, A'hern R, Agarwal JP, Shrivastava SK, Dinshaw KA. Females with paired occurrence of cancers in the UADT and genital region have a higher frequency of either Glutathione S-transferase M1/T1 null genotype. J Carcinog. 2005 Mar 24; 4(1):6. PMID: 15790417; PMCID: PMC1079904.
      Citations:    
    43. Hope Q, Bullock S, Evans C, Meitz J, Hamel N, Edwards SM, Severi G, Dearnaley D, Jhavar S, Southgate C, Falconer A, Dowe A, Muir K, Houlston RS, Engert JC, Roquis D, Sinnett D, Simard J, Heimdal K, M?ller P, Maehle L, Badzioch M, Eeles RA, Easton DF, English DR, Southey MC, Hopper JL, Foulkes WD, Giles GG, Cancer Research UK/British Association of Urological Surgeons' Section of Oncology Collaborators. Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2005 Feb; 14(2):397-402. PMID: 15734964.
      Citations:    
    44. Edwards S, Campbell C, Flohr P, Shipley J, Giddings I, Te-Poele R, Dodson A, Foster C, Clark J, Jhavar S, Kovacs G, Cooper CS. Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer. Br J Cancer. 2005 Jan 31; 92(2):376-81. PMID: 15583692; PMCID: PMC2361840.
      Citations:    
    45. Foster CS, Falconer A, Dodson AR, Norman AR, Dennis N, Fletcher A, Southgate C, Dowe A, Dearnaley D, Jhavar S, Eeles R, Feber A, Cooper CS. Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome. Oncogene. 2004 Aug 05; 23(35):5871-9. PMID: 15184867.
      Citations: 76     Fields:    Translation:Humans
    46. Jhavar S, Sarin R, Mulherkar R, Benner A, Agarwal JP, Dinshaw K. Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobacco. Oral Oncol. 2004 Jan; 40(1):84-91. PMID: 14662420.
      Citations: 7     Fields:    Translation:Humans
    47. Jhavar S, Agarwal JP, Naresh KN, Shrivastava SK, Borges AM, Dinshaw KA. Primary extranodal mucosa associated lymphoid tissue (MALT) lymphoma of the prostate. Leuk Lymphoma. 2001 Apr; 41(3-4):445-9. PMID: 11378561.
      Citations: 10     Fields:    Translation:Humans
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