"Lipocalin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lipocalin of approximately 200 amino acids that functions as an iron transporter and is expressed by cells of BONE MARROW and many other cells with secretory functions. It is involved in APOPTOSIS and may function to limit pathogenic bacterial growth as part of the INNATE IMMUNE RESPONSE.
| Descriptor ID |
D000071068
|
| MeSH Number(s) |
D12.776.124.050.475 D12.776.157.469.325 D12.776.624.664.700.123
|
| Concept/Terms |
Lipocalin-2- Lipocalin-2
- Lipocalin 2
- NGAL Protein
- Oncogene 24p3 Protein
- Siderocalin Protein
- Neutrophil Gelatinase-Associated Lipocalin
- Neutrophil Gelatinase Associated Lipocalin
- Lipocalin-2 Protein
- Lipocalin 2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Lipocalin-2".
Below are MeSH descriptors whose meaning is more specific than "Lipocalin-2".
This graph shows the total number of publications written about "Lipocalin-2" by people in this website by year, and whether "Lipocalin-2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Lipocalin-2" by people in Profiles.
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Inflammation Mediated by Gut Microbiome Alterations Promotes Lung Cancer Development and an Immunosuppressed Tumor Microenvironment. Cancer Immunol Res. 2024 Dec 03; 12(12):1736-1752.
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Predictive value of neutrophil gelatinase-associated lipocalin (NGAL) values for cardiac arrest outcomes: A systematic review and meta-analysis. Am J Emerg Med. 2024 06; 80:221-223.
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Systemic Neutrophil Gelatinase-Associated Lipocalin Alterations in Chronic Pancreatitis: A Multicenter, Cross-Sectional Study. Clin Transl Gastroenterol. 2024 Apr 01; 15(4):e00686.
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Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer. Sci Adv. 2022 10 14; 8(41):eabo5224.
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Neutrophil gelatinase-associated lipocalin is elevated in children with acute kidney injury and sickle cell anemia, and predicts mortality. Kidney Int. 2022 10; 102(4):885-893.
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Urine ALCAM, PF4 and VCAM-1 Surpass Conventional Metrics in Identifying Nephritis Disease Activity in Childhood-Onset Systemic Lupus Erythematosus. Front Immunol. 2022; 13:885307.
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Aptamer-Based Screen of Neuropsychiatric Lupus Cerebrospinal Fluid Reveals Potential Biomarkers That Overlap With the Choroid Plexus Transcriptome. Arthritis Rheumatol. 2022 07; 74(7):1223-1234.
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A targetable LIFR-NF-?B-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis. Nat Commun. 2021 12 17; 12(1):7333.
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Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion. Mol Oncol. 2021 10; 15(10):2752-2765.
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Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10; 22(16).