"Receptor, Notch4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor and proto-oncogene protein characterized by a large extracellular domain that consists of 29 EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats) and five ANKYRIN REPEATS. It functions as a receptor for SERRATE-JAGGED PROTEINS and Delta1 (DLK1) protein to control cell fate determination.
| Descriptor ID |
D000074562
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| MeSH Number(s) |
D12.776.543.750.725.937 D12.776.624.664.700.815 D12.776.930.770.937
|
| Concept/Terms |
Receptor, Notch4- Receptor, Notch4
- Notch4 Receptor
- Notch4 Protein
- Notch-4 Protein
- Notch 4 Protein
- Notch-4 Receptor
- Notch 4 Receptor
- Receptor, Notch-4
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch4".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch4".
This graph shows the total number of publications written about "Receptor, Notch4" by people in this website by year, and whether "Receptor, Notch4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptor, Notch4" by people in Profiles.
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Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome. Sci Rep. 2020 10 22; 10(1):18051.
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NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers. Mol Oncol. 2020 03; 14(3):504-519.
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Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines. Cancer Lett. 2018 08 01; 428:12-20.
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Notch4 promotes gastric cancer growth through activation of Wnt1/?-catenin signaling. Mol Cell Biochem. 2015 Mar; 401(1-2):165-74.
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ETS factors regulate Vegf-dependent arterial specification. Dev Cell. 2013 Jul 15; 26(1):45-58.
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Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy. Am J Physiol Renal Physiol. 2013 Apr 15; 304(8):F1127-36.
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Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res. 2009 Mar 15; 69(6):2400-7.
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Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc Natl Acad Sci U S A. 2004 Mar 09; 101(10):3338-45.
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Assignment of the murine Notch2 and Notch3 genes to chromosomes 3 and 17. Genomics. 1998 Apr 01; 49(1):160-1.