Receptor, Macrophage Colony-Stimulating Factor
"Receptor, Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.
| Descriptor ID |
D016186
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.500 D12.776.543.750.630.492 D12.776.543.750.705.852.150.150 D12.776.543.750.750.400.200.200 D12.776.624.664.700.800
|
| Concept/Terms |
Receptor, Macrophage Colony-Stimulating Factor- Receptor, Macrophage Colony-Stimulating Factor
- Receptor, Macrophage Colony Stimulating Factor
- Macrophage Colony-Stimulating Factor Receptors
- Macrophage Colony Stimulating Factor Receptors
- c-fms Protein
- c fms Protein
- Receptor, CSF-1
- Receptor, CSF 1
- Receptors, CSF-1
- CSF-1 Receptors
- Receptors, CSF 1
- CD115 Antigens
- Proto-Oncogene Protein fms
- M-CSF Receptors
- Receptors, M-CSF
- Receptors, M CSF
- Receptors, Macrophage Colony-Stimulating Factor
- Receptors, Macrophage Colony Stimulating Factor
- CD115 Antigen
- Antigen, CD115
- Antigens, CD115
- CSF-1 Receptor
- fms Proto-Oncogene Protein
- Proto-Oncogene Protein, fms
- fms Proto Oncogene Protein
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Macrophage Colony-Stimulating Factor".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Transferases [D08.811.913]
- Phosphotransferases [D08.811.913.696]
- Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
- Protein Kinases [D08.811.913.696.620.682]
- Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
- Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
- Receptor, Macrophage Colony-Stimulating Factor [D08.811.913.696.620.682.725.400.500]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.630.492]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.705.852.150.150]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.750.400.200.200]
- Neoplasm Proteins [D12.776.624]
- Oncogene Proteins [D12.776.624.664]
- Proto-Oncogene Proteins [D12.776.624.664.700]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.624.664.700.800]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Receptor, Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Receptor, Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Macrophage Colony-Stimulating Factor" by people in Profiles.
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Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers. Nat Commun. 2026 Jan 03; 17(1):1193.
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De novo pathogenic CSF1R variant implicates microglial dysfunction in pathogenesis of febrile infection-related epilepsy syndrome. Epilepsia. 2025 Sep; 66(9):e211-e218.
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Treatment of tenosynovial giant cell tumor and pigmented villonodular synovitis. Curr Opin Oncol. 2011 Jul; 23(4):361-6.
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Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation. J Biol Chem. 1994 Dec 02; 269(48):30659-67.
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Expression of c-myc and c-fms oncogenes in trophoblastic cells in hydatidiform mole and normal human placenta. J Clin Pathol. 1993 Mar; 46(3):204-7.
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Primary listerial infections are exacerbated in mice administered neutralizing antibody to macrophage colony-stimulating factor. J Immunol. 1992 Jul 01; 149(1):188-93.