"Receptors, Interleukin-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High affinity receptors for INTERLEUKIN-3. They are found on early HEMATOPOIETIC PROGENITOR CELLS; progenitors of MYELOID CELLS; EOSINOPHILS; and BASOPHILS. Interleukin-3 receptors are formed by the dimerization of the INTERLEUKIN-3 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR COMMON BETA SUBUNIT.
| Descriptor ID |
D016185
|
| MeSH Number(s) |
D12.776.543.750.705.852.150.360 D12.776.543.750.705.852.420.340 D12.776.543.750.750.400.200.480
|
| Concept/Terms |
Receptors, Interleukin-3- Receptors, Interleukin-3
- Receptors, Interleukin 3
- IL-3 Receptors
- IL 3 Receptors
- Receptors, IL-3
- Receptors, IL 3
- IL3 Receptors
- Receptors, IL3
- Interleukin-3 Receptor
- Interleukin 3 Receptor
- Receptor, Interleukin-3
- Interleukin-3 Receptors
- Interleukin 3 Receptors
- IL-3 Receptor
- IL 3 Receptor
- Receptor, IL-3
- IL3 Receptor
- Receptor, IL3
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-3".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
- Receptors, Interleukin-3 [D12.776.543.750.705.852.150.360]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-3 [D12.776.543.750.705.852.420.340]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
- Receptors, Interleukin-3 [D12.776.543.750.750.400.200.480]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-3".
This graph shows the total number of publications written about "Receptors, Interleukin-3" by people in this website by year, and whether "Receptors, Interleukin-3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 2 | 3 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Interleukin-3" by people in Profiles.
-
Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity. J Med Chem. 2015 Nov 25; 58(22):8970-84.
-
SL-401 and SL-501, targeted therapeutics directed at the interleukin-3 receptor, inhibit the growth of leukaemic cells and stem cells in advanced phase chronic myeloid leukaemia. Br J Haematol. 2014 Sep; 166(6):862-74.
-
Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients. Blood. 2014 Jul 17; 124(3):385-92.
-
Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus. PLoS Pathog. 2012; 8(6):e1002770.
-
Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population. Neurosci Lett. 2008 Jul 25; 440(1):35-7.
-
BCR-ABL oncogenic transformation of NIH 3T3 fibroblasts requires the IL-3 receptor. Oncogene. 2008 May 15; 27(22):3194-200.
-
TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood. 2003 Jun 15; 101(12):5007-9.
-
Down-regulation of interleukin-3/granulocyte-macrophage colony-stimulating factor receptor beta-chain in BCR-ABL(+) human leukemic cells: association with loss of cytokine-mediated Stat-5 activation and protection from apoptosis after BCR-ABL inhibition. Blood. 2001 May 01; 97(9):2846-53.
-
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J. 1995 Jun 15; 14(12):2816-26.
-
The murine interleukin-3 receptor alpha subunit gene: chromosomal localization, genomic structure, and promoter function. Blood. 1995 Mar 01; 85(5):1246-53.