Receptors, Interleukin-12
"Receptors, Interleukin-12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for INTERLEUKIN-12. They exist as dimers of beta 1 and beta 2 subunits. Signaling from interleukin-12 receptors occurs through their interaction with JANUS KINASES.
| Descriptor ID |
D053707
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.580
|
| Concept/Terms |
Receptors, Interleukin-12- Receptors, Interleukin-12
- Receptors, Interleukin 12
- Interleukin-12 Receptor
- Interleukin 12 Receptor
- IL-12 Receptor
- IL 12 Receptor
- Receptor, IL-12
- Receptor, Interleukin-12
- Receptor, Interleukin 12
- IL-12 Receptors
- IL 12 Receptors
- Receptors, IL-12
- Interleukin-12 Receptors
- Interleukin 12 Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-12".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-12".
This graph shows the total number of publications written about "Receptors, Interleukin-12" by people in this website by year, and whether "Receptors, Interleukin-12" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Interleukin-12" by people in Profiles.
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Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus. Arthritis Rheumatol. 2014 Dec; 66(12):3521-3.
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A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Hum Mol Genet. 2012 Feb 15; 21(4):926-33.
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Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med. 2009 Jun 11; 360(24):2544-55.
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Colocalization of the IL-12 receptor and FcgammaRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-gamma. Blood. 2008 Apr 15; 111(8):4173-83.
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An alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells. PLoS Med. 2006 Jan; 3(1):e11.
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Src homology 2-containing inositol 5'-phosphatase 1 negatively regulates IFN-gamma production by natural killer cells stimulated with antibody-coated tumor cells and interleukin-12. Cancer Res. 2005 Oct 01; 65(19):9099-107.
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RNA editing of interleukin-12 receptor beta2, 2451 C-to-U (Ala 604 Val) conversion, associated with atopy. Clin Exp Allergy. 2004 Mar; 34(3):363-8.
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IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells. J Clin Invest. 2002 Oct; 110(7):983-92.
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Atopy and mutations of IL-12 receptor beta 2 chain gene. Clin Exp Allergy. 2001 Aug; 31(8):1189-93.
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Reduced interferon-gamma production and mutations of the interleukin-12 receptor beta(2) chain gene in atopic subjects. Int Arch Allergy Immunol. 2001 Jan-Mar; 124(1-3):117-20.