"Killer Cells, Natural" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
| Descriptor ID |
D007694
|
| MeSH Number(s) |
A11.118.637.555.567.537 A15.145.229.637.555.567.537 A15.382.490.555.567.537
|
| Concept/Terms |
Killer Cells, Natural- Killer Cells, Natural
- NK Cells
- Cell, NK
- Cells, NK
- NK Cell
- Natural Killer Cells
- Cell, Natural Killer
- Cells, Natural Killer
- Killer Cell, Natural
- Natural Killer Cell
|
Below are MeSH descriptors whose meaning is more general than "Killer Cells, Natural".
Below are MeSH descriptors whose meaning is more specific than "Killer Cells, Natural".
This graph shows the total number of publications written about "Killer Cells, Natural" by people in this website by year, and whether "Killer Cells, Natural" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 0 | 1 |
| 2002 | 5 | 5 | 10 |
| 2003 | 1 | 3 | 4 |
| 2004 | 5 | 2 | 7 |
| 2005 | 4 | 0 | 4 |
| 2006 | 4 | 0 | 4 |
| 2007 | 2 | 3 | 5 |
| 2008 | 4 | 2 | 6 |
| 2009 | 2 | 3 | 5 |
| 2010 | 2 | 2 | 4 |
| 2011 | 4 | 3 | 7 |
| 2012 | 4 | 1 | 5 |
| 2013 | 4 | 3 | 7 |
| 2014 | 7 | 1 | 8 |
| 2015 | 6 | 3 | 9 |
| 2016 | 8 | 2 | 10 |
| 2017 | 10 | 3 | 13 |
| 2018 | 6 | 1 | 7 |
| 2019 | 14 | 1 | 15 |
| 2020 | 3 | 9 | 12 |
| 2021 | 3 | 5 | 8 |
| 2022 | 2 | 5 | 7 |
| 2023 | 0 | 13 | 13 |
| 2024 | 4 | 6 | 10 |
| 2025 | 7 | 1 | 8 |
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Below are the most recent publications written about "Killer Cells, Natural" by people in Profiles.
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TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength. Cancer Immunol Res. 2025 Oct 01; 13(10):1576-1590.
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Next-generation multiplex-edited CAR-NK cells: more edits, more power? J Immunother Cancer. 2025 Sep 15; 13(9).
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Comparison of the Cytotoxicity, Internalization and Anti-Cancer Drug Delivery Efficacy of Nature Killer Cell Derived Nanovesicles and Extracellular Vesicles. Int J Nanomedicine. 2025; 20:10683-10700.
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Constitutive IL-7 signaling promotes CAR-NK cell survival in the solid tumor microenvironment but impairs tumor control. J Immunother Cancer. 2025 Jul 23; 13(7).
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High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19. JCI Insight. 2025 Jul 08; 10(13).
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Exercise-induced ?2-adrenergic receptor activation enhances effector lymphocyte mobilization in humans and suppresses lymphoma growth in mice through NK-cells. Brain Behav Immun. 2025 Aug; 128:751-765.
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Clinical, immunologic, and genetic characteristics of 148 patients with natural killer cell deficiency. J Allergy Clin Immunol. 2025 May; 155(5):1623-1634.
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The Golgi complex governs natural killer cell lytic granule positioning to promote directionality in cytotoxicity. Cell Rep. 2025 01 28; 44(1):115156.
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Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells. Cell Rep. 2025 01 28; 44(1):115122.
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FT538, iPSC-derived NK cells, enhance AML cell killing when combined with chemotherapy. J Cell Mol Med. 2025 Jan; 29(1):e70169.