"Killer Cells, Natural" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
Descriptor ID |
D007694
|
MeSH Number(s) |
A11.118.637.555.567.537 A15.145.229.637.555.567.537 A15.382.490.555.567.537
|
Concept/Terms |
Killer Cells, Natural- Killer Cells, Natural
- NK Cells
- Cell, NK
- Cells, NK
- NK Cell
- Natural Killer Cells
- Cell, Natural Killer
- Cells, Natural Killer
- Killer Cell, Natural
- Natural Killer Cell
|
Below are MeSH descriptors whose meaning is more general than "Killer Cells, Natural".
Below are MeSH descriptors whose meaning is more specific than "Killer Cells, Natural".
This graph shows the total number of publications written about "Killer Cells, Natural" by people in this website by year, and whether "Killer Cells, Natural" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 2 | 3 |
1995 | 1 | 1 | 2 |
1996 | 6 | 1 | 7 |
1997 | 2 | 5 | 7 |
1998 | 2 | 3 | 5 |
1999 | 2 | 5 | 7 |
2000 | 5 | 1 | 6 |
2001 | 2 | 3 | 5 |
2002 | 5 | 6 | 11 |
2003 | 3 | 7 | 10 |
2004 | 9 | 12 | 21 |
2005 | 19 | 5 | 24 |
2006 | 6 | 6 | 12 |
2007 | 5 | 7 | 12 |
2008 | 7 | 6 | 13 |
2009 | 3 | 8 | 11 |
2010 | 5 | 10 | 15 |
2011 | 5 | 8 | 13 |
2012 | 7 | 4 | 11 |
2013 | 12 | 5 | 17 |
2014 | 15 | 8 | 23 |
2015 | 12 | 5 | 17 |
2016 | 16 | 6 | 22 |
2017 | 16 | 7 | 23 |
2018 | 11 | 5 | 16 |
2019 | 19 | 6 | 25 |
2020 | 10 | 11 | 21 |
2021 | 11 | 8 | 19 |
2022 | 2 | 8 | 10 |
2023 | 0 | 12 | 12 |
2024 | 1 | 5 | 6 |
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Below are the most recent publications written about "Killer Cells, Natural" by people in Profiles.
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Identification of Specific Cell Surface Markers on Immune Cells of Squirrel Monkeys (Saimiri sciureus). J Immunol Res. 2024; 2024:8215195.
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?-Actin G342D as a Cause of NK Cell Deficiency Impairing Lytic Synapse Termination. J Immunol. 2024 Mar 15; 212(6):962-973.
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Results of a phase I trial with Haploidentical mbIL-21 ex vivo expanded NK cells for patients with multiply relapsed and refractory AML. Am J Hematol. 2024 May; 99(5):890-899.
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Adoptive cellular therapy after hematopoietic stem cell transplantation. Am J Hematol. 2024 May; 99(5):910-921.
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Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors: a phase 1/2 trial. Nat Med. 2024 Mar; 30(3):772-784.
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Vitamin B6 Competition in the Tumor Microenvironment Hampers Antitumor Functions of NK Cells. Cancer Discov. 2024 01 12; 14(1):176-193.
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Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies. Iran J Immunol. 2023 12 31; 20(4):410-426.
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Ex Vivo Expanded Cord Blood Natural Killer Cells Combined with Rituximab and High-Dose Chemotherapy and Autologous Stem Cell Transplantation for B Cell Non-Hodgkin Lymphoma. Transplant Cell Ther. 2024 Feb; 30(2):203.e1-203.e9.
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NK Cell Therapeutics for Hematologic Malignancies: from Potential to Fruition. Curr Hematol Malig Rep. 2023 Dec; 18(6):264-272.
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Human PLCG2 haploinsufficiency results in a novel natural killer cell immunodeficiency. J Allergy Clin Immunol. 2024 01; 153(1):216-229.