"Receptors, TIE" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION, PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain Ig and EGF domains.
Descriptor ID |
D042764
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MeSH Number(s) |
D08.811.913.696.620.682.725.400.925 D12.776.543.750.630.687
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Concept/Terms |
Receptors, TIE- Receptors, TIE
- TIE Receptors
- Receptor Tyrosine Kinase TIE
- TIE Receptor Family
- Family, TIE Receptor
- Receptor Family, TIE
- TIE Receptor Tyrosine Kinase
- TIE Receptor Tyrosine Kinases
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Below are MeSH descriptors whose meaning is more general than "Receptors, TIE".
Below are MeSH descriptors whose meaning is more specific than "Receptors, TIE".
This graph shows the total number of publications written about "Receptors, TIE" by people in this website by year, and whether "Receptors, TIE" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 2 | 2 |
2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, TIE" by people in Profiles.
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Prognostic significance of Tie-1 protein expression in patients with early chronic phase chronic myeloid leukemia. Cancer. 2002 Mar 01; 94(5):1517-21.
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High expression of the receptor tyrosine kinase Tie-1 in acute myeloid leukemia and myelodysplastic syndrome. Leuk Lymphoma. 2001 Jul; 42(3):511-6.
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Clinical relevance of Flt1 and Tie1 angiogenesis receptors expression in B-cell chronic lymphocytic leukemia (CLL). Leuk Res. 2001 Apr; 25(4):279-85.