"Receptor, trkC" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is specific for NEUROTROPHIN 3. It is widely expressed in nervous tissue and may play a role in mediating the effects of NEUROTROPHIN 3 on the proliferation and differentiation of NEURONS.
| Descriptor ID |
D020812
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.800 D12.776.543.750.630.499 D12.776.543.750.750.400.550.700
|
| Concept/Terms |
Receptor, trkC- Receptor, trkC
- trkC Receptor
- NTRK3 Receptor
- Receptor, NTRK3
- Receptor, Neurotrophic Tyrosine Kinase Type 3
- NTRK3 Protein
- trkC Protein
- Neurotrophic Tyrosine Kinase Receptor Type 3
- Neurotrophin 3 Receptor
- Receptor, Neurotrophin 3
- Protein-Tyrosine Kinase TRKC
- Kinase TRKC, Protein-Tyrosine
- Protein Tyrosine Kinase TRKC
- TRKC, Protein-Tyrosine Kinase
|
Below are MeSH descriptors whose meaning is more general than "Receptor, trkC".
Below are MeSH descriptors whose meaning is more specific than "Receptor, trkC".
This graph shows the total number of publications written about "Receptor, trkC" by people in this website by year, and whether "Receptor, trkC" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptor, trkC" by people in Profiles.
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Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma. J Clin Pathol. 2024 Oct 20; 77(11):751-755.
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ETV6::NTRK3-associated papillary adenocarcinoma: let us play it by ear. Virchows Arch. 2024 Dec; 485(6):1161-1165.
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A, B, C's of Trk Receptors and Their Ligands in Ocular Repair. Int J Mol Sci. 2022 Nov 15; 23(22).
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Diagnostic testing approaches for the identification of patients with TRK fusion cancer prior to enrollment in clinical trials investigating larotrectinib. Cancer Genet. 2022 01; 260-261:46-52.
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Patient-driven discovery and post-clinical validation of NTRK3 fusion as an acquired resistance mechanism to selpercatinib in RET fusion-positive lung cancer. Ann Oncol. 2021 06; 32(6):817-819.
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Targeting TRK family proteins in cancer. Pharmacol Ther. 2017 May; 173:58-66.
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FGFR1 and NTRK3 actionable alterations in "Wild-Type" gastrointestinal stromal tumors. J Transl Med. 2016 12 14; 14(1):339.
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TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior. Oncogene. 2013 Aug 08; 32(32):3698-710.
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Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study. J Pathol. 2012 Sep; 228(1):119-30.
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Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Dev Biol. 2012 Apr 15; 364(2):114-27.