"Receptor, trkC" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is specific for NEUROTROPHIN 3. It is widely expressed in nervous tissue and may play a role in mediating the effects of NEUROTROPHIN 3 on the proliferation and differentiation of NEURONS.
| Descriptor ID |
D020812
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.800 D12.776.543.750.630.499 D12.776.543.750.750.400.550.700
|
| Concept/Terms |
Receptor, trkC- Receptor, trkC
- trkC Receptor
- NTRK3 Receptor
- Receptor, NTRK3
- Receptor, Neurotrophic Tyrosine Kinase Type 3
- NTRK3 Protein
- trkC Protein
- Neurotrophic Tyrosine Kinase Receptor Type 3
- Neurotrophin 3 Receptor
- Receptor, Neurotrophin 3
- Protein-Tyrosine Kinase TRKC
- Kinase TRKC, Protein-Tyrosine
- Protein Tyrosine Kinase TRKC
- TRKC, Protein-Tyrosine Kinase
|
Below are MeSH descriptors whose meaning is more general than "Receptor, trkC".
Below are MeSH descriptors whose meaning is more specific than "Receptor, trkC".
This graph shows the total number of publications written about "Receptor, trkC" by people in this website by year, and whether "Receptor, trkC" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, trkC" by people in Profiles.
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Efficacy and safety of entrectinib in children with extracranial solid or central nervous system (CNS) tumours harbouring NTRK or ROS1 fusions. Eur J Cancer. 2025 May 02; 220:115308.
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Secretory Carcinoma with ETV6-NTRK3 Gene Fusion and Lymph Node Metastasis in Maxillary Gingiva: A Case Report with Pathological and Molecular Correlative Studies. Ann Clin Lab Sci. 2023 Sep; 53(5):800-805.
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A, B, C's of Trk Receptors and Their Ligands in Ocular Repair. Int J Mol Sci. 2022 Nov 15; 23(22).
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Adjuvant Maintenance Larotrectinib Therapy in 2 Children With NTRK Fusion-positive High-grade Cancers. J Pediatr Hematol Oncol. 2021 Oct 01; 43(7):e987-e990.
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Pan-Trk immunohistochemistry reliably identifies ETV6-NTRK3 fusion in secretory carcinoma of the salivary gland. Virchows Arch. 2020 Feb; 476(2):295-305.
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Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer. Cancer Res. 2017 07 01; 77(13):3502-3512.
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Congenital mesoblastic nephroma: a study of 19 cases using immunohistochemistry and ETV6-NTRK3 fusion gene rearrangement. Pathology. 2016 Jan; 48(1):47-50.
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CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Mol Cell. 2008 Dec 05; 32(5):718-26.
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Mutational analysis of the tyrosine kinome in colorectal cancers. Science. 2003 May 09; 300(5621):949.
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Congenital-infantile fibrosarcoma. A clinicopathologic study of 10 cases and molecular detection of the ETV6-NTRK3 fusion transcripts using paraffin-embedded tissues. Am J Clin Pathol. 2001 Mar; 115(3):348-55.