Receptor, Ciliary Neurotrophic Factor
"Receptor, Ciliary Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for CILIARY NEUROTROPHIC FACTOR. They are heterotrimeric proteins formed by the association of the CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA SUBUNIT with the LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130. Although the receptor regulates neuronal development, it is structurally similar to the cytokine receptor for INTERLEUKIN-6; (RECEPTORS, INTERLEUKIN-6).
| Descriptor ID |
D020801
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| MeSH Number(s) |
D12.776.543.750.750.400.550.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptor, Ciliary Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Ciliary Neurotrophic Factor".
This graph shows the total number of publications written about "Receptor, Ciliary Neurotrophic Factor" by people in this website by year, and whether "Receptor, Ciliary Neurotrophic Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptor, Ciliary Neurotrophic Factor" by people in Profiles.
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Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain. Neuroscience. 1999 Mar; 90(3):815-21.
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Selective inhibition of kindling development by intraventricular administration of TrkB receptor body. J Neurosci. 1999 Feb 15; 19(4):1424-36.
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Activation loop tyrosines contribute varying roles to TrkB autophosphorylation and signal transduction. Oncogene. 1998 Apr 02; 16(13):1691-700.
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Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. EMBO J. 1995 Jul 03; 14(13):3116-26.
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Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor. Genomics. 1995 Jan 01; 25(1):157-63.