"Cytokine Receptor gp130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine receptor that contains extracellular FIBRONECTIN TYPE III DOMAINS which mediate its function through the formation of oligomeric complexes with itself, or with a variety of CYTOKINE RECEPTORS. It does not bind IL-6, but activates JANUS KINASES and STAT3 TRANSCRIPTION FACTOR.
| Descriptor ID |
D050822
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.400.500 D12.776.543.750.705.852.420.560.249 D12.776.543.750.705.852.555.600.500 D12.776.543.750.705.852.583.500 D12.776.543.750.750.400.550.250.500
|
| Concept/Terms |
Cytokine Receptor gp130- Cytokine Receptor gp130
- gp130, Cytokine Receptor
- IL-6 Receptor Signal Transducer gp130
- IL6ST gp130
- gp130 Transducing Protein
- Signal Transducer gp130
- gp130, Signal Transducer
- Antigens, CD130
- gp130 Signal Transducer
- Signal Transducer, gp130
- gp130 IL-6 Family Receptor
- gp130 IL 6 Family Receptor
- IL-6 Family Receptor gp130
- CD130 Antigens
- Interleukin-6 Receptor Subunit Beta
- Interleukin 6 Receptor Subunit Beta
- Signal-Transducing Receptor gp130
- Receptor gp130, Signal-Transducing
- Signal Transducing Receptor gp130
- gp130, Signal-Transducing Receptor
|
Below are MeSH descriptors whose meaning is more general than "Cytokine Receptor gp130".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-6 [D12.776.543.750.705.852.420.400]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.400.500]
- Receptors, Interleukin-11 [D12.776.543.750.705.852.420.560]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.560.249]
- Receptors, Oncostatin M [D12.776.543.750.705.852.555]
- Receptors, Oncostatin M, Type II [D12.776.543.750.705.852.555.600]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.555.600.500]
- Receptors, OSM-LIF [D12.776.543.750.705.852.583]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.583.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
- Receptor, Ciliary Neurotrophic Factor [D12.776.543.750.750.400.550.250]
- Cytokine Receptor gp130 [D12.776.543.750.750.400.550.250.500]
Below are MeSH descriptors whose meaning is more specific than "Cytokine Receptor gp130".
This graph shows the total number of publications written about "Cytokine Receptor gp130" by people in this website by year, and whether "Cytokine Receptor gp130" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 1 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cytokine Receptor gp130" by people in Profiles.
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The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Immunity. 2023 05 09; 56(5):979-997.e11.
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Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome. J Allergy Clin Immunol. 2021 08; 148(2):585-598.
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Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome. J Exp Med. 2020 06 01; 217(6).
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Innate Stat3-mediated induction of the antimicrobial protein Reg3? is required for host defense against MRSA pneumonia. J Exp Med. 2013 Mar 11; 210(3):551-61.
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Dependency of colorectal cancer on a TGF-?-driven program in stromal cells for metastasis initiation. Cancer Cell. 2012 Nov 13; 22(5):571-84.
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Cell type-specific STAT3 activation by gp130-related cytokines in the peripheral nerves. Neuroreport. 2009 May 06; 20(7):663-8.
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Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress. Biochem Biophys Res Commun. 2009 May 01; 382(2):445-50.
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Interleukin-6 is required for the early induction of glial fibrillary acidic protein in Schwann cells during Wallerian degeneration. J Neurochem. 2009 Feb; 108(3):776-86.
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A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells. J Neurochem. 2009 Jan; 108(1):273-84.
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Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteoclastogenic signals generated by IL-6-type cytokines. J Cell Biochem. 2000 Sep 14; 79(4):532-41.