"Cytokine Receptor gp130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine receptor that contains extracellular FIBRONECTIN TYPE III DOMAINS which mediate its function through the formation of oligomeric complexes with itself, or with a variety of CYTOKINE RECEPTORS. It does not bind IL-6, but activates JANUS KINASES and STAT3 TRANSCRIPTION FACTOR.
| Descriptor ID |
D050822
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.400.500 D12.776.543.750.705.852.420.560.249 D12.776.543.750.705.852.555.600.500 D12.776.543.750.705.852.583.500 D12.776.543.750.750.400.550.250.500
|
| Concept/Terms |
Cytokine Receptor gp130- Cytokine Receptor gp130
- gp130, Cytokine Receptor
- IL-6 Receptor Signal Transducer gp130
- IL6ST gp130
- gp130 Transducing Protein
- Signal Transducer gp130
- gp130, Signal Transducer
- Antigens, CD130
- gp130 Signal Transducer
- Signal Transducer, gp130
- gp130 IL-6 Family Receptor
- gp130 IL 6 Family Receptor
- IL-6 Family Receptor gp130
- CD130 Antigens
- Interleukin-6 Receptor Subunit Beta
- Interleukin 6 Receptor Subunit Beta
- Signal-Transducing Receptor gp130
- Receptor gp130, Signal-Transducing
- Signal Transducing Receptor gp130
- gp130, Signal-Transducing Receptor
|
Below are MeSH descriptors whose meaning is more general than "Cytokine Receptor gp130".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-6 [D12.776.543.750.705.852.420.400]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.400.500]
- Receptors, Interleukin-11 [D12.776.543.750.705.852.420.560]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.560.249]
- Receptors, Oncostatin M [D12.776.543.750.705.852.555]
- Receptors, Oncostatin M, Type II [D12.776.543.750.705.852.555.600]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.555.600.500]
- Receptors, OSM-LIF [D12.776.543.750.705.852.583]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.583.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
- Receptor, Ciliary Neurotrophic Factor [D12.776.543.750.750.400.550.250]
- Cytokine Receptor gp130 [D12.776.543.750.750.400.550.250.500]
Below are MeSH descriptors whose meaning is more specific than "Cytokine Receptor gp130".
This graph shows the total number of publications written about "Cytokine Receptor gp130" by people in this website by year, and whether "Cytokine Receptor gp130" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 1 | 3 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cytokine Receptor gp130" by people in Profiles.
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Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling. Cell Rep Med. 2024 Aug 20; 5(8):101658.
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The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Immunity. 2023 05 09; 56(5):979-997.e11.
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Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. Cancer Res. 2021 10 15; 81(20):5336-5352.
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Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome. J Allergy Clin Immunol. 2021 08; 148(2):585-598.
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Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome. J Exp Med. 2020 06 01; 217(6).
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Protein and glycomic plasma markers for early detection of adenoma and colon cancer. Gut. 2018 03; 67(3):473-484.
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Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway. Stem Cells. 2015 Aug; 33(8):2400-15.
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Innate Stat3-mediated induction of the antimicrobial protein Reg3? is required for host defense against MRSA pneumonia. J Exp Med. 2013 Mar 11; 210(3):551-61.
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Dependency of colorectal cancer on a TGF-?-driven program in stromal cells for metastasis initiation. Cancer Cell. 2012 Nov 13; 22(5):571-84.
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Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. Genes Dev. 2010 Aug 15; 24(16):1731-45.