"Wnt Signaling Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN.
| Descriptor ID |
D060449
|
| MeSH Number(s) |
G02.111.820.925 G04.835.925
|
| Concept/Terms |
Wnt Signaling Pathway- Wnt Signaling Pathway
- Pathway, Wnt Signaling
- Pathways, Wnt Signaling
- Signaling Pathway, Wnt
- Signaling Pathways, Wnt
- Wnt Signaling Pathways
- Wnt Pathway
- Pathway, Wnt
- Pathways, Wnt
- Wnt Pathways
Wnt beta-Catenin Signaling Pathway- Wnt beta-Catenin Signaling Pathway
- Wnt beta Catenin Signaling Pathway
- Wnt Pathway, Canonical
- Canonical Wnt Pathway
- Canonical Wnt Pathways
- Pathway, Canonical Wnt
- Pathways, Canonical Wnt
- Wnt Pathways, Canonical
|
Below are MeSH descriptors whose meaning is more general than "Wnt Signaling Pathway".
Below are MeSH descriptors whose meaning is more specific than "Wnt Signaling Pathway".
This graph shows the total number of publications written about "Wnt Signaling Pathway" by people in this website by year, and whether "Wnt Signaling Pathway" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 3 | 4 |
| 2012 | 4 | 2 | 6 |
| 2013 | 8 | 6 | 14 |
| 2014 | 4 | 4 | 8 |
| 2015 | 2 | 5 | 7 |
| 2016 | 5 | 6 | 11 |
| 2017 | 4 | 5 | 9 |
| 2018 | 2 | 2 | 4 |
| 2019 | 2 | 5 | 7 |
| 2020 | 1 | 4 | 5 |
| 2021 | 3 | 6 | 9 |
| 2022 | 0 | 5 | 5 |
| 2023 | 3 | 3 | 6 |
| 2024 | 2 | 2 | 4 |
| 2025 | 1 | 4 | 5 |
| 2026 | 2 | 6 | 8 |
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Below are the most recent publications written about "Wnt Signaling Pathway" by people in Profiles.
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Daam2 phosphorylation by CK2a negatively regulates Wnt activity during white matter development and injury. Proc Natl Acad Sci U S A. 2023 08 29; 120(35):e2304112120.
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A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis. Cancer Res. 2021 09 01; 81(17):4441-4454.
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Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes. J Biol Chem. 2021 Jan-Jun; 296:100488.
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Daam2 couples translocation and clustering of Wnt receptor signalosomes through Rac1. J Cell Sci. 2021 01 25; 134(2).
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DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway. J Genet Genomics. 2020 06 20; 47(6):301-310.
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FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation. Cancer Res. 2018 08 01; 78(15):4229-4240.
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WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis. Dev Cell. 2017 11 20; 43(4):436-448.e6.
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Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing. PLoS Genet. 2017 Jul; 13(7):e1006870.
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Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression. Oncogene. 2017 10 26; 36(43):5958-5968.
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MYC Mediates mRNA Cap Methylation of Canonical Wnt/?-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase. Mol Cancer Res. 2017 02; 15(2):213-224.