"Wnt Signaling Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN.
| Descriptor ID |
D060449
|
| MeSH Number(s) |
G02.111.820.925 G04.835.925
|
| Concept/Terms |
Wnt Signaling Pathway- Wnt Signaling Pathway
- Pathway, Wnt Signaling
- Pathways, Wnt Signaling
- Signaling Pathway, Wnt
- Signaling Pathways, Wnt
- Wnt Signaling Pathways
- Wnt Pathway
- Pathway, Wnt
- Pathways, Wnt
- Wnt Pathways
Wnt beta-Catenin Signaling Pathway- Wnt beta-Catenin Signaling Pathway
- Wnt beta Catenin Signaling Pathway
- Wnt Pathway, Canonical
- Canonical Wnt Pathway
- Canonical Wnt Pathways
- Pathway, Canonical Wnt
- Pathways, Canonical Wnt
- Wnt Pathways, Canonical
|
Below are MeSH descriptors whose meaning is more general than "Wnt Signaling Pathway".
Below are MeSH descriptors whose meaning is more specific than "Wnt Signaling Pathway".
This graph shows the total number of publications written about "Wnt Signaling Pathway" by people in this website by year, and whether "Wnt Signaling Pathway" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 3 | 4 |
| 2012 | 3 | 2 | 5 |
| 2013 | 8 | 6 | 14 |
| 2014 | 3 | 4 | 7 |
| 2015 | 2 | 5 | 7 |
| 2016 | 5 | 6 | 11 |
| 2017 | 5 | 6 | 11 |
| 2018 | 2 | 1 | 3 |
| 2019 | 2 | 6 | 8 |
| 2020 | 1 | 4 | 5 |
| 2021 | 3 | 6 | 9 |
| 2022 | 1 | 4 | 5 |
| 2023 | 4 | 3 | 7 |
| 2024 | 2 | 2 | 4 |
| 2025 | 1 | 5 | 6 |
| 2026 | 0 | 3 | 3 |
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Below are the most recent publications written about "Wnt Signaling Pathway" by people in Profiles.
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Loss of ZNRF3/RNF43 unleashes EGFR in cancer. Elife. 2026 Apr 10; 13.
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Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders. Mol Cell. 2026 Feb 19; 86(4):604-624.e16.
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miR-302 regulates pancreatic progenitor pool and pancreatic size. Biol Open. 2026 Jan 01; 15(1).
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Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer's Disease. J Neurosci. 2025 12 03; 45(49).
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Targeting FZD6 creates therapeutically actionable vulnerabilities for advanced prostate cancer. Oncogene. 2025 Dec; 44(50):4868-4877.
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Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling. Dev Biol. 2025 12; 528:34-56.
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Modeling post-gastrula development via bidirectional pluripotent stem cells. Cell Res. 2025 Dec; 35(12):954-969.
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One Wnt to lead them all: a Wnt1 primer. Differentiation. 2025 Jul-Aug; 144:100884.
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Catalpol Protects Against Retinal Ischemia Through Antioxidation, Anti-Ischemia, Downregulation of ?-Catenin, VEGF, and Angiopoietin-2: In Vitro and In Vivo Studies. Int J Mol Sci. 2025 Apr 24; 26(9).
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Genetic variants in canonical Wnt signaling pathway associated with pediatric immune thrombocytopenia. Blood Adv. 2024 11 12; 8(21):5529-5538.