Mechanotransduction, Cellular
"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
| Descriptor ID |
D040542
|
| MeSH Number(s) |
G01.154.090.500 G02.111.820.580 G04.835.580
|
| Concept/Terms |
Mechanotransduction, Cellular- Mechanotransduction, Cellular
- Signal Transduction, Mechanical
- Mechanical Signal Transduction
- Cellular Mechanotransduction
- Mechanosensory Transduction
- Transduction, Mechanosensory
|
Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".
Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".
This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in this website by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 3 | 0 | 3 |
| 2007 | 4 | 0 | 4 |
| 2008 | 3 | 0 | 3 |
| 2009 | 2 | 2 | 4 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 4 | 2 | 6 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 3 | 0 | 3 |
| 2018 | 4 | 3 | 7 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 2 | 2 | 4 |
| 2023 | 3 | 0 | 3 |
| 2024 | 0 | 3 | 3 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles.
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Mechano-Signal Transduction Pathways of the Diaphragmatic Muscle and Role of Cytoskeleton. Genes (Basel). 2025 Aug 18; 16(8).
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Sensing the Stiffness: Cellular Mechano-Sensing at the Implant Interface. Cells. 2025 Jul 17; 14(14).
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Oncogenic KRAS Mutations Confer a Unique Mechanotransduction Response to Peristalsis in Colorectal Cancer Cells. Mol Cancer Res. 2025 Feb 06; 23(2):128-142.
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A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling. Nat Cardiovasc Res. 2024 Jul; 3(7):785-798.
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Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation. Nat Neurosci. 2024 May; 27(5):913-926.
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PIEZO ion channels: force sensors of the interoceptive nervous system. J Physiol. 2024 Oct; 602(19):4777-4788.
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PIEZO2 in somatosensory neurons controls gastrointestinal transit. Cell. 2023 08 03; 186(16):3386-3399.e15.
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Labeling PIEZO2 activity in the peripheral nervous system. Neuron. 2023 08 16; 111(16):2488-2501.e8.
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Excessive mechanotransduction in sensory neurons causes joint contractures. Science. 2023 01 13; 379(6628):201-206.
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Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals. Elife. 2022 11 29; 11.