Interleukin-11 Receptor alpha Subunit
"Interleukin-11 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A low affinity interleukin-11 receptor subunit that combines with the CYTOKINE RECEPTOR GP130 to form a high affinity receptor for INTERLEUKIN-11. Multiple isoforms of this protein exist due to ALTERNATIVE SPLICING of its MRNA.
| Descriptor ID |
D053703
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.560.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-11 Receptor alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-11 Receptor alpha Subunit".
This graph shows the total number of publications written about "Interleukin-11 Receptor alpha Subunit" by people in this website by year, and whether "Interleukin-11 Receptor alpha Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Interleukin-11 Receptor alpha Subunit" by people in Profiles.
-
BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation. Proc Natl Acad Sci U S A. 2017 07 25; 114(30):8065-8070.
-
Rare and low-frequency coding variants alter human adult height. Nature. 2017 02 09; 542(7640):186-190.
-
Targeting the interleukin-11 receptor a in metastatic prostate cancer: A first-in-man study. Cancer. 2015 Jul 15; 121(14):2411-21.
-
Genetically modified T cells targeting interleukin-11 receptor a-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases. Cancer Res. 2012 Jan 01; 72(1):271-81.
-
The interleukin-11 receptor alpha as a candidate ligand-directed target in osteosarcoma: consistent data from cell lines, orthotopic models, and human tumor samples. Cancer Res. 2009 Mar 01; 69(5):1995-9.
-
Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer. Cancer Res. 2004 Jan 15; 64(2):435-9.