"Receptor, IGF Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.
| Descriptor ID |
D017526
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.185 D12.776.543.750.630.468 D12.776.543.750.750.400.780.400
|
| Concept/Terms |
Receptor, IGF Type 1- Receptor, IGF Type 1
- Receptors, IGF-1
- IGF-1 Receptors
- Receptors, IGF 1
- IGF-1 Receptor
- IGF 1 Receptor
- Receptor, IGF-1
- Receptors, Insulin-Like-Growth Factor I
- IGF-I Receptor
- IGF I Receptor
- Receptor, Insulin-Like Growth Factor Type 1
- Receptor, IGF-I
- Receptor, IGF I
- Receptor, Insulin-Like Growth Factor I
- Insulin-Like-Growth Factor I Receptor
- Insulin Like Growth Factor I Receptor
- IGF Type 1 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, IGF Type 1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, IGF Type 1".
This graph shows the total number of publications written about "Receptor, IGF Type 1" by people in this website by year, and whether "Receptor, IGF Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 2 | 0 | 2 |
| 1996 | 2 | 0 | 2 |
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 3 | 4 |
| 2000 | 1 | 1 | 2 |
| 2001 | 3 | 0 | 3 |
| 2002 | 2 | 3 | 5 |
| 2003 | 4 | 2 | 6 |
| 2004 | 2 | 1 | 3 |
| 2005 | 3 | 2 | 5 |
| 2006 | 4 | 6 | 10 |
| 2007 | 7 | 1 | 8 |
| 2008 | 3 | 3 | 6 |
| 2009 | 8 | 4 | 12 |
| 2010 | 4 | 4 | 8 |
| 2011 | 9 | 7 | 16 |
| 2012 | 7 | 3 | 10 |
| 2013 | 9 | 5 | 14 |
| 2014 | 5 | 11 | 16 |
| 2015 | 5 | 5 | 10 |
| 2016 | 1 | 5 | 6 |
| 2017 | 2 | 4 | 6 |
| 2018 | 1 | 2 | 3 |
| 2019 | 4 | 0 | 4 |
| 2020 | 3 | 5 | 8 |
| 2021 | 2 | 3 | 5 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptor, IGF Type 1" by people in Profiles.
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Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
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Pathways to precision medicine: deciphering the secrets of physiological and pathological atrial enlargement. Clin Sci (Lond). 2024 Sep 18; 138(18):1173-1177.
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Competing Engagement of ?-arrestin Isoforms Balances IGF1R/p53 Signaling and Controls Melanoma Cell Chemotherapeutic Responsiveness. Mol Cancer Res. 2023 12 01; 21(12):1288-1302.
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Integrated DNA Copy Number and Expression Profiling Identifies IGF1R as a Prognostic Biomarker in Pediatric Osteosarcoma. Int J Mol Sci. 2022 Jul 21; 23(14).
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SIRPa Mediates IGF1 Receptor in Cardiomyopathy Induced by Chronic Kidney Disease. Circ Res. 2022 07 22; 131(3):207-221.
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Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Nat Commun. 2021 09 06; 12(1):5296.
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Germline variation in the insulin-like growth factor pathway and risk of Barrett's esophagus and esophageal adenocarcinoma. Carcinogenesis. 2021 04 17; 42(3):369-377.
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CASC11 promotes aggressiveness of prostate cancer cells through miR-145/IGF1R axis. Prostate Cancer Prostatic Dis. 2021 09; 24(3):891-902.
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The Role of IGF/IGF-1R Signaling in Hepatocellular Carcinomas: Stemness-Related Properties and Drug Resistance. Int J Mol Sci. 2021 Feb 16; 22(4).
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FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K. Am J Physiol Heart Circ Physiol. 2021 04 01; 320(4):H1470-H1485.