"Receptor, IGF Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor that is specific for IGF-II and mannose-6-phosphate. The receptor is a 250-kDa single chain polypeptide which is unrelated in structure to the type 1 IGF receptor (RECEPTOR, IGF TYPE 1) and does not have a tyrosine kinase domain.
| Descriptor ID |
D017527
|
| MeSH Number(s) |
D12.776.543.750.750.400.780.410
|
| Concept/Terms |
Receptor, IGF Type 2- Receptor, IGF Type 2
- IGF-2 Receptor
- IGF 2 Receptor
- Receptor, IGF-2
- IGF-II Receptor
- IGF II Receptor
- Insulin-Like-Growth-Factor II Receptor
- Insulin Like Growth Factor II Receptor
- Receptor, Insulin-Like-Growth-Factor II
- Mannose-6-Phosphate Receptor
- Mannose 6 Phosphate Receptor
- Receptor, Insulin-Like Growth Factor II
- Receptor, Insulin Like Growth Factor II
- Receptor, Insulin-Like Growth Factor Type 2
- Receptor, Insulin Like Growth Factor Type 2
- Receptor, Mannose-6-Phosphate
- Receptor, Mannose 6 Phosphate
- Receptors, IGF-2
- IGF-2 Receptors
- Receptors, IGF 2
- Receptors, Insulin-Like Growth Factor II
- Receptors, Insulin Like Growth Factor II
- IGF Type 2 Receptor
- Receptor, IGF-II
- Receptor, IGF II
|
Below are MeSH descriptors whose meaning is more general than "Receptor, IGF Type 2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, IGF Type 2".
This graph shows the total number of publications written about "Receptor, IGF Type 2" by people in this website by year, and whether "Receptor, IGF Type 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, IGF Type 2" by people in Profiles.
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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation. Nat Commun. 2023 07 03; 14(1):3911.
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Two unrelated children with overlapping 6q25.3 deletions, motor speech disorders, and language delays. Am J Med Genet A. 2017 Oct; 173(10):2659-2669.
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Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. Urology. 2013 Jul; 82(1):253.e9-15.
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R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis. PLoS One. 2011; 6(10):e26060.
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IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas. Int J Cancer. 2009 Dec 01; 125(11):2673-8.
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Reduced in vitro functional activity of human NRAMP1 (SLC11A1) allele that predisposes to increased risk of pediatric tuberculosis disease. Genes Immun. 2007 Dec; 8(8):691-8.
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Tissue-specific inactivation of murine M6P/IGF2R. Am J Pathol. 2003 Jan; 162(1):321-8.
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M6P/IGF2R tumor suppressor gene mutated in hepatocellular carcinomas in Japan. Hepatology. 2002 May; 35(5):1153-63.
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Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations. Hum Mutat. 2001; 18(1):25-31.
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Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: A study of the TGRbetaRII, BAX, hMSH3, hMSH6, IGFIIR and BLM genes. Int J Cancer. 2000 May 20; 89(3):230-5.