"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
| Descriptor ID |
D001343
|
| MeSH Number(s) |
G04.146.399 G04.417.350.091
|
| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Macro-autophagy
- Macro autophagy
- Macro-autophagies
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
- Macroautophagy
- Macroautophagies
- Autophagocytosis
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
- Autophagic Programmed Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 8 | 0 | 8 |
| 2008 | 6 | 1 | 7 |
| 2009 | 5 | 2 | 7 |
| 2010 | 5 | 6 | 11 |
| 2011 | 9 | 1 | 10 |
| 2012 | 11 | 5 | 16 |
| 2013 | 14 | 7 | 21 |
| 2014 | 15 | 8 | 23 |
| 2015 | 10 | 4 | 14 |
| 2016 | 18 | 9 | 27 |
| 2017 | 17 | 11 | 28 |
| 2018 | 14 | 12 | 26 |
| 2019 | 9 | 11 | 20 |
| 2020 | 16 | 7 | 23 |
| 2021 | 7 | 9 | 16 |
| 2022 | 1 | 6 | 7 |
| 2023 | 3 | 8 | 11 |
| 2024 | 7 | 3 | 10 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Autophagy" by people in Profiles.
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The autophagy protein ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy. Elife. 2025 Mar 18; 13.
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Investigation of dynamic regulation of TFEB nuclear shuttling by microfluidics and quantitative modelling. Commun Biol. 2025 Mar 15; 8(1):443.
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Castration-resistant prostate cancer is resensitized to androgen deprivation by autophagy-dependent apoptosis induced by blocking SKP2. Sci Signal. 2024 Dec 17; 17(867):eadk4122.
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Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation. Commun Biol. 2024 Nov 21; 7(1):1554.
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MTOR maintains endothelial cell integrity to limit lung vascular injury. J Biol Chem. 2024 Dec; 300(12):107952.
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USF2 and TFEB compete in regulating lysosomal and autophagy genes. Nat Commun. 2024 Sep 27; 15(1):8334.
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The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB. Mol Pharmacol. 2024 Sep 17; 106(4):164-172.
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Crizotinib Enhances PARP Inhibitor Efficacy in Ovarian Cancer Cells and Xenograft Models by Inducing Autophagy. Mol Cancer Res. 2024 09 04; 22(9):840-851.
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Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer. Elife. 2024 Aug 30; 13.
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TFEB safeguards trophoblast syncytialization in humans and mice. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2404062121.