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ANDREW CHU

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6701 FANNIN
Houston, TX 77030
ORCID ORCID Icon0000-0002-8824-2914 Additional info
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    Collapse Biography 
    Collapse education and training
    Children's Hospital of Philadelphia, Philadelphia, PAResearch Fellowship06/2011Gastroenterology (Cell Biology)
    Children's Hospital of Philadelphia, Philadelphia, PAFellowship06/2010Pediatric Gastroenterology
    Cincinnati Children's Hospital Medical Center, Cincinnati, OHResidency06/2007General Pediatrics
    Baylor College of Medicine, Houston, TXMD05/2004Medicine
    Princeton University, Princeton, NJAB05/1999Public and International Affairs
    Collapse awards and honors
    2023Department of Pediatrics Chair's Outstanding Clinician Award, Baylor College of Medicine
    2022 - 2023Ambulatory Practitioner Award for Excellence in Patient Experience, Texas Children's Hospital
    2022 - 2025Faculty Senator (School of Medicine), Baylor College of Medicine
    2020 - 2023Houstonia Magazine Top Doctors, Houstonia Magazine
    2019Early Career Faculty Award for Excellence in Patient Care, Baylor College of Medicine
    2013Liver Scholar Award, American Association for the Study of Liver Diseases/Alpha-1 Foundation
    2009Alexander M. White, III Postdoctoral Research Fellowship Award, American Liver Foundation
    2008Pediatric Scientist Development Program (PSDP) Fellowship, NIH/NICHD
    2006Outstanding Resident Award, Cincinnati Pediatric Society

    Collapse Overview 
    Collapse overview
    Dr. Chu serves as Attending Physician in Pediatric Gastroenterology at Texas Children’s Hospital and is Associate Professor of Pediatrics at Baylor College of Medicine and Faculty Senator for its School of Medicine. His clinical and research interests focus on the evaluation and management of children with disorders of gut-brain interaction (DGBIs, also known as functional abdominal disorders). This served as his motivation to co-found and serve as Clinical Lead for the Multidisciplinary Abdominal Pain Program (MAPP) at Texas Children’s Hospital. This is a collaborative initiative involving Gastroenterology, Anesthesiology, Psychology, Nutrition, and Physical Therapy that provides quaternary consultative services for children suffering from DGBIs. In addition to these responsibilities, he provides general gastroenterology care at Texas Children's Hospital The Woodlands, where he also serves as Clinical Lead for the Multidisciplinary Feeding Clinic, a collaborative initiative involving Gastroenterology, Speech Language Pathology, Occupational Therapy, and Nutrition to provide outpatient evaluation and management of children with chronic feeding difficulties. He is active in endoscopic procedural education for the Gastroenterology Fellowship program and also has a rich background in basic science laboratory research, in which he previously studied the molecular mechanisms of alpha-1-antitrypsin deficiency-associated liver disease and biliary atresia. He has been recognized by Baylor College of Medicine and Texas Children's Hospital with some of their highest clinical recognitions for his exceptional clinical care, including the Department of Pediatrics Chair's Outstanding Clinician Award and the Ambulatory Practitioner Award for Excellence in Patient Experience.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rudnick DA, Huang J, Hidvegi T, Chu AS, Hale P, Munanairi A, Dietzen DJ, Cliften PF, Tycksen E, Lutkewitte AJ, Finck BN, Pak SC, Silverman GA, Perlmutter DH. Regulation of PGC1a Downstream of the Insulin Signaling Pathway Plays a Role in the Hepatic Proteotoxicity of Mutant a1-Antitrypsin Deficiency Variant Z. Gastroenterology. 2022 07; 163(1):270-284. PMID: 35301011; PMCID: PMC9232923.
      Citations:    Fields:    Translation:AnimalsCells
    2. Chu AS, Torres L, Kao G, Gilbert C, Monico EC, Chumpitazi BP. Multidisciplinary Care for Refractory Pediatric Functional Abdominal Pain Decreases Emergency and Inpatient Utilization. J Pediatr Gastroenterol Nutr. 2022 02 01; 74(2):248-252. PMID: 34560729; PMCID: PMC8799479.
      Citations:    Fields:    Translation:Humans
    3. . A Preliminary Study of the Impact of a Multidisciplinary Clinic Intervention on Emergency Department and Inpatient Utilization by Children with Functional Abdominal Pain. Gastroenterology. 2019; 156(6):S-580.
    4. Wang Y, Cobanoglu MC, Li J, Hidvegi T, Hale P, Ewing M, Chu AS, Gong Z, Muzumdar R, Pak SC, Silverman GA, Bahar I, Perlmutter DH. An analog of glibenclamide selectively enhances autophagic degradation of misfolded a1-antitrypsin Z. PLoS One. 2019; 14(1):e0209748. PMID: 30673724; PMCID: PMC6343872.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    5. Chu AS, Chopra KB, Perlmutter DH. Is severe progressive liver disease caused by alpha-1-antitrypsin deficiency more common in children or adults? Liver Transpl. 2016 07; 22(7):886-94. PMID: 26946192.
      Citations: 13     Fields:    Translation:Humans
    6. Mukherjee A, Chakraborty S, Wang Y, CHU A, Perlmutter D. Alpha-1-Antitrypsin Deficiency: Role in Health and Disease. Liver disease in α1-antitrypsin deficiency. 2016.
    7. Perlmutter DH, Chopra K, Chu A. Two New Considerations for Improving the Diagnosis of a1-Antitrypsin Deficiency-Associated Liver Disease. Dig Dis Sci. 2015 Jun; 60(6):1511-3. PMID: 25634676; PMCID: PMC4456220.
      Citations: 2     Fields:    Translation:Humans
    8. Perlmutter D, CHU A, Chopra K. Liver Disease From Alpha-1-Antitrypsin Deficiency: What Therapeutic Options Are in the Pipeline?. 2015. View Publication.
    9. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 329.5: Superior Mesenteric Artery Syndrome (Wilkie Syndrome, Cast Syndrome, Arteriomesenteric Duodenal Compression Syndrome). 2015.
    10. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 330.1: Ileus. 2015.
    11. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 330.2: Adhesions. 2015.
    12. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 330.4: Closed-Loop Obstructions. 2015.
    13. Chu AS, Perlmutter DH, Wang Y. Capitalizing on the autophagic response for treatment of liver disease caused by alpha-1-antitrypsin deficiency and other genetic diseases. Biomed Res Int. 2014; 2014:459823. PMID: 25025052; PMCID: PMC4065733.
      Citations: 7     Fields:    Translation:Humans
    14. Ghouse R, Chu A, Wang Y, Perlmutter DH. Mysteries of a1-antitrypsin deficiency: emerging therapeutic strategies for a challenging disease. Dis Model Mech. 2014 Apr; 7(4):411-9. PMID: 24719116; PMCID: PMC3974452.
      Citations: 20     Fields:    Translation:HumansAnimals
    15. Chu AS, Russo PA, Wells RG. Cholangiocyte cilia are abnormal in syndromic and non-syndromic biliary atresia. Mod Pathol. 2012 May; 25(5):751-7. PMID: 22301700; PMCID: PMC3341539.
      Citations: 17     Fields:    Translation:HumansCells
    16. Shin S, Walton G, Aoki R, Brondell K, Schug J, Fox A, Smirnova O, Dorrell C, Erker L, Chu AS, Wells RG, Grompe M, Greenbaum LE, Kaestner KH. Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev. 2011 Jun 01; 25(11):1185-92. PMID: 21632825; PMCID: PMC3110956.
      Citations: 72     Fields:    Translation:AnimalsCells
    17. Chu AS, Diaz R, Hui JJ, Yanger K, Zong Y, Alpini G, Stanger BZ, Wells RG. Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis. Hepatology. 2011 May; 53(5):1685-95. PMID: 21520179; PMCID: PMC3082729.
      Citations: 97     Fields:    Translation:AnimalsCells
    18. CHU A. Netter’s Pediatrics. Chapter 107: Gastritis and Gastrointestinal Bleeding. 2011.
    19. CHU A. Netter’s Pediatrics. Chapter 108: Intestinal Obstruction and Malrotation. 2011.
    20. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 329.5: Superior Mesenteric Artery Syndrome (Wilkie Syndrome, Cast Syndrome, Arteriomesenteric Duodenal Compression Syndrome). 2011.
    21. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 330.1: Ileus. 2011.
    22. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 330.2: Adhesions. 2011.
    23. CHU A and Liacouras C. Nelson Textbook of Pediatrics. Chapter 330.4: Closed-Loop Obstructions. 2011.
    24. Chu AS, Friedman JR. A role for microRNA in cystic liver and kidney diseases. J Clin Invest. 2008 Nov; 118(11):3585-7. PMID: 18949060; PMCID: PMC2571036.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    25. Moffett BS, Schmees L, Zinser K, Erikson C, CHU A, Strobel N. . Evaluation of intravenous ranitidine for gastric acid suppression in critically ill pediatric patients. (Accepted April 2019). The Journal of Pediatric Pharmacology and Therapeutics.
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