Site-Specific DNA-Methyltransferase (Adenine-Specific)
"Site-Specific DNA-Methyltransferase (Adenine-Specific)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.
Descriptor ID |
D015265
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MeSH Number(s) |
D08.811.913.555.500.350.700
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Concept/Terms |
Site-Specific DNA-Methyltransferase (Adenine-Specific)- Site-Specific DNA-Methyltransferase (Adenine-Specific)
- DNA Modification Methylases Adenine Specific
- DNA Modification Methylases (Adenine-Specific)
- Modification Methylases (Adenine-Specific)
- Site Specific Methyltransferases (Adenine Specific)
- Site-Specific Methyltransferases (Adenine-Specific)
- DNA-Adenine Methylases
- DNA Adenine Methylases
- Methylases, DNA-Adenine
- Modification Methylases (Adenine Specific)
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Below are MeSH descriptors whose meaning is more general than "Site-Specific DNA-Methyltransferase (Adenine-Specific)".
Below are MeSH descriptors whose meaning is more specific than "Site-Specific DNA-Methyltransferase (Adenine-Specific)".
This graph shows the total number of publications written about "Site-Specific DNA-Methyltransferase (Adenine-Specific)" by people in this website by year, and whether "Site-Specific DNA-Methyltransferase (Adenine-Specific)" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Site-Specific DNA-Methyltransferase (Adenine-Specific)" by people in Profiles.
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Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase. ACS Chem Biol. 2023 04 21; 18(4):734-745.
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Whole genome sequencing identifies candidate genes for familial essential tremor and reveals biological pathways implicated in essential tremor aetiology. EBioMedicine. 2022 Nov; 85:104290.
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Clostridioides difficile specific DNA adenine methyltransferase CamA squeezes and flips adenine out of DNA helix. Nat Commun. 2021 06 08; 12(1):3436.
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The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site. Nat Commun. 2019 10 10; 10(1):4600.
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Research resource: The estrogen receptor a cistrome defined by DamIP. Mol Endocrinol. 2012 Feb; 26(2):349-57.
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DamIP: using mutant DNA adenine methyltransferase to study DNA-protein interactions in vivo. Curr Protoc Mol Biol. 2011 Apr; Chapter 21:Unit21.21.
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Association between an estrogen receptor alpha gene polymorphism and the risk of prostate cancer in black men. J Urol. 2006 Feb; 175(2):523-7.
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Cholesteryl ester transfer protein TaqIB polymorphism in the cholesterol and recurrent events study. Curr Atheroscler Rep. 2005 May; 7(3):178-9.
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Cloning and characterization of the Bg/II restriction-modification system reveals a possible evolutionary footprint. Gene. 1997 Mar 10; 187(1):19-27.
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The XmnI restriction-modification system: cloning, expression, sequence organization and similarity between the R and M genes. Gene. 1996 Sep 16; 173(2):121-7.