"Interleukin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
| Descriptor ID |
D007375
|
| MeSH Number(s) |
D12.644.276.374.465.010 D12.644.276.374.500.400 D12.776.467.374.465.010 D12.776.467.374.500.400 D23.529.374.465.131 D23.529.374.500.400
|
| Concept/Terms |
Interleukin-1- Interleukin-1
- Interleukin 1
- IL-1
- T Helper Factor
- Lymphocyte-Activating Factor
- Lymphocyte Activating Factor
- Macrophage Cell Factor
- Epidermal Cell Derived Thymocyte-Activating Factor
- Epidermal Cell Derived Thymocyte Activating Factor
- Interleukin I
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-1".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1".
This graph shows the total number of publications written about "Interleukin-1" by people in this website by year, and whether "Interleukin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 3 | 5 |
| 1996 | 2 | 3 | 5 |
| 1997 | 1 | 3 | 4 |
| 1998 | 0 | 6 | 6 |
| 1999 | 2 | 4 | 6 |
| 2000 | 4 | 5 | 9 |
| 2001 | 4 | 4 | 8 |
| 2002 | 3 | 10 | 13 |
| 2003 | 4 | 9 | 13 |
| 2004 | 2 | 5 | 7 |
| 2005 | 4 | 6 | 10 |
| 2006 | 3 | 4 | 7 |
| 2007 | 0 | 2 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 2 | 2 |
| 2012 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interleukin-1" by people in Profiles.
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Cytokine Profiling of Erythroderma Biopsies Reveals Types 2 and 17 Immune Activation Status. J Cutan Pathol. 2025 Mar; 52(3):235-243.
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IL-36 Staining Distinguishes Clear Cell Acanthoma From Psoriasis. Am J Dermatopathol. 2024 Aug 01; 46(8):549-551.
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Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-37. Ocul Surf. 2024 Apr; 32:182-191.
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A TNF-IL-1 circuit controls Yersinia within intestinal pyogranulomas. J Exp Med. 2024 Mar 04; 221(3).
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Imbalanced IL-37/TNF-a/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro. Ocul Surf. 2022 10; 26:234-243.
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Genome-wide association study of circulating interleukin 6 levels identifies novel loci. Hum Mol Genet. 2021 04 27; 30(5):393-409.
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IL-36 in chronic inflammation and fibrosis - bridging the gap? J Clin Invest. 2021 01 19; 131(2).
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Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies. Cytotherapy. 2020 09; 22(9):474-481.
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IL-37/ STAT3/ HIF-1a negative feedback signaling drives gemcitabine resistance in pancreatic cancer. Theranostics. 2020; 10(9):4088-4100.
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RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model. Prostate. 2020 02; 80(2):133-145.