"Interleukin-1alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
| Descriptor ID |
D053582
|
| MeSH Number(s) |
D12.644.276.374.465.010.300 D12.644.276.374.500.400.300 D12.776.467.374.465.010.300 D12.776.467.374.500.400.300 D23.529.374.465.131.300 D23.529.374.500.400.300
|
| Concept/Terms |
Interleukin-1alpha- Interleukin-1alpha
- Interleukin 1alpha
- IL-1 alpha
- Interleukin-1 alpha
- Interleukin 1 alpha
- Hematopoietin-1
- Hematopoietin 1
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-1alpha".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1alpha".
This graph shows the total number of publications written about "Interleukin-1alpha" by people in this website by year, and whether "Interleukin-1alpha" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-1alpha" by people in Profiles.
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Chemotherapy-induced activation of caspase-1 and IL-1a release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation. Nat Commun. 2026 Apr 20; 17(1).
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Dismantling the tumoral cloak of self-protection. PLoS Biol. 2023 05; 21(5):e3002104.
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ELF3 mediates IL-1a induced differentiation of mesenchymal stem cells to inflammatory iCAFs. Stem Cells. 2021 12; 39(12):1766-1777.
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Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor. Mol Cell. 2016 09 15; 63(6):976-89.
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A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk of recurrence in patients with oropharyngeal cancer. Oncotarget. 2016 Jun 07; 7(23):34472-9.
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Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV. J Neurovirol. 2016 08; 22(4):431-41.
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A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk and HPV-positive tumours of oropharyngeal cancer. Eur J Cancer. 2015 Jul; 51(11):1415-23.
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Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma. Clin Cancer Res. 2012 Oct 01; 18(19):5329-40.
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KrasG12D-induced IKK2/?/NF-?B activation by IL-1a and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 2012 Jan 17; 21(1):105-20.