"Interleukin-1beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.
| Descriptor ID |
D053583
|
| MeSH Number(s) |
D12.644.276.374.465.010.600 D12.644.276.374.500.400.600 D12.776.467.374.465.010.600 D12.776.467.374.500.400.600 D23.529.374.465.131.600 D23.529.374.500.400.600
|
| Concept/Terms |
Interleukin-1beta- Interleukin-1beta
- Interleukin 1beta
- IL-1 beta
- Interleukin-1 beta
- Interleukin 1 beta
- Catabolin
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-1beta".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1beta".
This graph shows the total number of publications written about "Interleukin-1beta" by people in this website by year, and whether "Interleukin-1beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2006 | 0 | 4 | 4 |
| 2007 | 5 | 6 | 11 |
| 2008 | 4 | 10 | 14 |
| 2009 | 2 | 11 | 13 |
| 2010 | 3 | 12 | 15 |
| 2011 | 2 | 5 | 7 |
| 2012 | 3 | 8 | 11 |
| 2013 | 2 | 6 | 8 |
| 2014 | 0 | 13 | 13 |
| 2015 | 5 | 5 | 10 |
| 2016 | 4 | 8 | 12 |
| 2017 | 3 | 6 | 9 |
| 2018 | 3 | 3 | 6 |
| 2019 | 6 | 6 | 12 |
| 2020 | 1 | 8 | 9 |
| 2021 | 2 | 6 | 8 |
| 2022 | 2 | 4 | 6 |
| 2023 | 1 | 3 | 4 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Interleukin-1beta" by people in Profiles.
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The IL-1? inhibitor canakinumab in previously treated lower-risk myelodysplastic syndromes: a phase 2 clinical trial. Nat Commun. 2024 Nov 13; 15(1):9840.
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LPS-induced whole-blood cytokine production and depressive symptoms in dementia spousal caregivers: The moderating effect of childhood trauma. Psychoneuroendocrinology. 2024 Oct; 168:107140.
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IL-1? promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells. Blood Adv. 2024 03 12; 8(5):1234-1249.
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D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1?-driven pyroptotic uroepithelial cell shedding in the murine bladder. Dev Cell. 2024 Jan 08; 59(1):33-47.e5.
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Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation. J Clin Invest. 2023 10 02; 133(19).
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Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model. Invest Ophthalmol Vis Sci. 2023 04 03; 64(4):8.
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Stool Interleukin-1? Differentiates Clostridioides difficile Infection (CDI) From Asymptomatic Carriage and Non-CDI Diarrhea. Clin Infect Dis. 2023 02 08; 76(3):e1467-e1475.
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Inhibition of interleukin-1? reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm. Nat Commun. 2022 09 13; 13(1):5346.
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The NLRP3 inflammasome fires up heme-induced inflammation in hemolytic conditions. Transl Res. 2023 02; 252:34-44.
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ESE3-positive PSCs drive pancreatic cancer fibrosis, chemoresistance and poor prognosis via tumour-stromal IL-1?/NF-?B/ESE3 signalling axis. Br J Cancer. 2022 11; 127(8):1461-1472.