"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
|
| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
|
| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 7 | 1 | 8 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 3 | 4 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 2 | 4 |
| 2003 | 0 | 6 | 6 |
| 2004 | 2 | 4 | 6 |
| 2005 | 1 | 1 | 2 |
| 2006 | 4 | 1 | 5 |
| 2007 | 3 | 3 | 6 |
| 2008 | 0 | 2 | 2 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 6 | 8 |
| 2011 | 1 | 3 | 4 |
| 2012 | 2 | 1 | 3 |
| 2013 | 5 | 0 | 5 |
| 2014 | 4 | 6 | 10 |
| 2015 | 2 | 2 | 4 |
| 2016 | 5 | 5 | 10 |
| 2017 | 1 | 5 | 6 |
| 2018 | 1 | 4 | 5 |
| 2019 | 3 | 2 | 5 |
| 2020 | 2 | 4 | 6 |
| 2021 | 0 | 3 | 3 |
| 2022 | 2 | 2 | 4 |
| 2023 | 2 | 2 | 4 |
| 2024 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury, enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent Treg-microglia crosstalk. Nat Neurosci. 2025 Mar; 28(3):499-516.
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Immunologic Profiling of CSF in Subarachnoid Neurocysticercosis Reveals Specific Interleukin-10-Producing Cell Populations During Treatment. Neurol Neuroimmunol Neuroinflamm. 2024 Nov; 11(6):e200320.
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Magnesium increases numbers of Foxp3+ Treg cells and reduces arthritis severity and joint damage in an IL-10-dependent manner mediated by the intestinal microbiome. EBioMedicine. 2023 Jun; 92:104603.
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Circulating Inflammatory Biomarkers Predict Pain Change Following Exercise-Induced Shoulder Injury: Findings From the Biopsychosocial Influence on Shoulder Pain Preclinical Trial. J Pain. 2023 08; 24(8):1465-1477.
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Acute high-fat diet impairs macrophage-supported intestinal damage resolution. JCI Insight. 2023 02 08; 8(3).
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Endogenous Interleukin-10 Contributes to Wound Healing and Regulates Tissue Repair. J Surg Res. 2023 05; 285:26-34.
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Dexmedetomidine Alters the Inflammatory Profile of Rat Microglia In Vitro. Neurocrit Care. 2023 06; 38(3):688-697.
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Cellular Sources and Neuroprotective Roles of Interleukin-10 in the Facial Motor Nucleus after Axotomy. Cells. 2022 10 09; 11(19).
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IL-10 and TNFa are associated with decreased survival in low-risk pediatric acute myeloid leukemia; a children's oncology group report. Pediatr Hematol Oncol. 2023 Mar; 40(2):147-158.
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IL-10 promotes endothelial progenitor cell infiltration and wound healing via STAT3. FASEB J. 2022 07; 36(7):e22298.