"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
|
| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
|
| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 3 | 1 | 4 |
| 1995 | 2 | 2 | 4 |
| 1996 | 4 | 1 | 5 |
| 1997 | 11 | 2 | 13 |
| 1998 | 2 | 7 | 9 |
| 1999 | 6 | 2 | 8 |
| 2000 | 3 | 8 | 11 |
| 2001 | 4 | 5 | 9 |
| 2002 | 4 | 6 | 10 |
| 2003 | 1 | 12 | 13 |
| 2004 | 7 | 14 | 21 |
| 2005 | 2 | 4 | 6 |
| 2006 | 9 | 7 | 16 |
| 2007 | 7 | 6 | 13 |
| 2008 | 6 | 7 | 13 |
| 2009 | 3 | 5 | 8 |
| 2010 | 2 | 9 | 11 |
| 2011 | 3 | 9 | 12 |
| 2012 | 5 | 3 | 8 |
| 2013 | 8 | 2 | 10 |
| 2014 | 5 | 13 | 18 |
| 2015 | 2 | 3 | 5 |
| 2016 | 6 | 6 | 12 |
| 2017 | 1 | 6 | 7 |
| 2018 | 2 | 5 | 7 |
| 2019 | 3 | 2 | 5 |
| 2020 | 4 | 6 | 10 |
| 2021 | 2 | 7 | 9 |
| 2022 | 3 | 3 | 6 |
| 2023 | 4 | 1 | 5 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature. 2024 Aug; 632(8023):182-191.
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LPS-induced whole-blood cytokine production and depressive symptoms in dementia spousal caregivers: The moderating effect of childhood trauma. Psychoneuroendocrinology. 2024 Oct; 168:107140.
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Interleukin-10 in cancer immunotherapy: from bench to bedside. Trends Cancer. 2023 09; 9(9):716-725.
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Magnesium increases numbers of Foxp3+ Treg cells and reduces arthritis severity and joint damage in an IL-10-dependent manner mediated by the intestinal microbiome. EBioMedicine. 2023 Jun; 92:104603.
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Mucosal immunization with lactiplantibacillus plantarum-displaying recombinant SARS-CoV-2 epitopes on the surface induces humoral and mucosal immune responses in mice. Microb Cell Fact. 2023 May 09; 22(1):96.
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Resolution of cisplatin-induced fatigue does not require endogenous interleukin-10 in male mice. Behav Brain Res. 2023 04 27; 444:114381.
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Acute high-fat diet impairs macrophage-supported intestinal damage resolution. JCI Insight. 2023 02 08; 8(3).
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Endogenous Interleukin-10 Contributes to Wound Healing and Regulates Tissue Repair. J Surg Res. 2023 05; 285:26-34.
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STAT3 Inhibits Autocrine IFN Signaling in Type I Conventional Dendritic Cells. J Immunol. 2022 10 01; 209(7):1286-1299.
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IL-10 and TNFa are associated with decreased survival in low-risk pediatric acute myeloid leukemia; a children's oncology group report. Pediatr Hematol Oncol. 2023 Mar; 40(2):147-158.