"Interleukin-18" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.
| Descriptor ID |
D020382
|
| MeSH Number(s) |
D12.644.276.374.465.518 D12.776.467.374.465.518 D23.529.374.465.518
|
| Concept/Terms |
Interleukin-18- Interleukin-18
- Interleukin 18
- IFN-gamma-Inducing Factor
- IL-18
- Interferon-gamma Inducing Factor
- Inducing Factor, Interferon-gamma
- Interferon gamma Inducing Factor
- Interferon-gamma-Inducing Factor
- IFN-gamma Inducing Factor
- IFN gamma Inducing Factor
- Inducing Factor, IFN-gamma
- IL18
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-18".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-18".
This graph shows the total number of publications written about "Interleukin-18" by people in this website by year, and whether "Interleukin-18" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 2 | 1 | 3 |
| 2008 | 3 | 3 | 6 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 3 | 0 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 2 | 3 | 5 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 3 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 4 | 4 |
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Below are the most recent publications written about "Interleukin-18" by people in Profiles.
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Association of interleukin-6 and interleukin-18 with cardiovascular disease in older adults: Atherosclerosis Risk in Communities study. Eur J Prev Cardiol. 2023 11 09; 30(16):1731-1740.
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No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice. Front Immunol. 2023; 14:1230050.
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Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model. Invest Ophthalmol Vis Sci. 2023 04 03; 64(4):8.
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Interleukin-18 as a severity marker and novel potential therapeutic target for epidermolytic ichthyosis. Clin Exp Dermatol. 2023 Mar 01; 48(3):199-210.
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IL-33 and IL-10 Serum Levels Increase in MCI Patients Following Homotaurine Treatment. Front Immunol. 2022; 13:813951.
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Interleukin-1? secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair. Gut Microbes. 2022 Jan-Dec; 14(1):2014772.
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Effects of placebo administration on immune mechanisms and relationships with central endogenous opioid neurotransmission. Mol Psychiatry. 2022 02; 27(2):831-839.
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Molecular mechanisms and functions of pyroptosis in inflammation and antitumor immunity. Mol Cell. 2021 11 18; 81(22):4579-4590.
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Telomere dysfunction instigates inflammation in inflammatory bowel disease. Proc Natl Acad Sci U S A. 2021 07 20; 118(29).
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A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021 07; 11(7):1661-1671.