"Interleukin-11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
| Descriptor ID |
D017370
|
| MeSH Number(s) |
D12.644.276.374.465.511 D12.776.467.374.465.511 D23.529.374.465.511
|
| Concept/Terms |
Interleukin-11- Interleukin-11
- Interleukin 11
- IL-11
- IL11
- Adipogenesis Inhibitory Factor
- Factor, Adipogenesis Inhibitory
- Inhibitory Factor, Adipogenesis
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-11".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-11".
This graph shows the total number of publications written about "Interleukin-11" by people in this website by year, and whether "Interleukin-11" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-11" by people in Profiles.
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Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo. PLoS One. 2014; 9(5):e95993.
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Treatment and prognosis of anaplastic thyroid carcinoma: experience from a single institution in China. PLoS One. 2013; 8(11):e80011.
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Dependency of colorectal cancer on a TGF-?-driven program in stromal cells for metastasis initiation. Cancer Cell. 2012 Nov 13; 22(5):571-84.
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Helicobacter pylori outer membrane proteins on gastric mucosal interleukin 6 and 11 expression in Mongolian gerbils. J Gastroenterol Hepatol. 2011 Nov; 26(11):1677-84.
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Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet. 2011 Jan 07; 88(1):6-18.
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Recombinant human interleukin-11 treatment enhances collateral vessel growth after femoral artery ligation. Arterioscler Thromb Vasc Biol. 2011 Feb; 31(2):306-12.
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Management of chemotherapy-induced thrombocytopenia: current status of thrombopoietic agents. Semin Hematol. 2009 Jan; 46(1 Suppl 2):S26-32.
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The effect of interleukin 11 on thrombocytopenia associated with tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. Cancer. 2008 Sep 15; 113(6):1338-43.
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Phase II study of low-dose interleukin-11 in patients with myelodysplastic syndrome. Leuk Lymphoma. 2006 Oct; 47(10):2049-54.
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COX-2 induces IL-11 production in human breast cancer cells. J Surg Res. 2006 Apr; 131(2):267-75.