Bone Marrow Stromal Antigen 2
"Bone Marrow Stromal Antigen 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GPI-linked membrane glycoprotein and antiviral factor that functions as a homodimer. It is induced by INTERFERON-GAMMA and blocks the release of enveloped mammalian viruses by directly tethering nascent VIRAL PARTICLES to the membranes of infected cells.
| Descriptor ID |
D000074010
|
| MeSH Number(s) |
D12.776.395.550.448.150 D12.776.543.484.500.150 D12.776.543.550.418.150
|
| Concept/Terms |
Bone Marrow Stromal Antigen 2- Bone Marrow Stromal Antigen 2
- Bone Marrow Stromal Cell Antigen 2
- Antigen, CD317
- Antigens, CD317
- CD317 Antigens
- Tetherin
- CD317 Antigen
|
Below are MeSH descriptors whose meaning is more general than "Bone Marrow Stromal Antigen 2".
Below are MeSH descriptors whose meaning is more specific than "Bone Marrow Stromal Antigen 2".
This graph shows the total number of publications written about "Bone Marrow Stromal Antigen 2" by people in this website by year, and whether "Bone Marrow Stromal Antigen 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bone Marrow Stromal Antigen 2" by people in Profiles.
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BST2 facilitates activation of hematopoietic stem cells through ERK signaling. Exp Hematol. 2024 Dec; 140:104653.
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Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin. Cell Rep. 2023 10 31; 42(10):113254.
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Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2. Cell Rep. 2020 12 22; 33(12):108530.
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The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy. J Biol Chem. 2015 Mar 13; 290(11):7269-79.
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Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction. J Exp Med. 2009 Jul 06; 206(7):1603-14.