"Paneth Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Differentiated epithelial cells of the INTESTINAL MUCOSA, found in the basal part of the intestinal crypts of Lieberkuhn. Paneth cells secrete GROWTH FACTORS, digestive enzymes such as LYSOZYME and antimicrobial peptides such as cryptdins (ALPHA-DEFENSINS) into the crypt lumen.
| Descriptor ID |
D019879
|
| MeSH Number(s) |
A03.556.124.369.700 A10.615.550.444.700 A11.436.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Paneth Cells".
Below are MeSH descriptors whose meaning is more specific than "Paneth Cells".
This graph shows the total number of publications written about "Paneth Cells" by people in this website by year, and whether "Paneth Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Paneth Cells" by people in Profiles.
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Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice. Microbiome. 2023 11 17; 11(1):256.
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Targeting Mitochondrial Damage as a Therapeutic for Ileal Crohn's Disease. Cells. 2021 05 29; 10(6).
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Ileocolonic Histopathological and Microbial Alterations in the Irritable Bowel Syndrome: A Nested Community Case-Control Study. Clin Transl Gastroenterol. 2020 12 22; 12(1):e00296.
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Paneth cells promote angiogenesis and regulate portal hypertension?in response to microbial signals. J Hepatol. 2020 09; 73(3):628-639.
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Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis. Gut. 2020 11; 69(11):1928-1938.
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Extracellular Vesicles with Possible Roles in Gut Intestinal Tract Homeostasis and IBD. Mediators Inflamm. 2020; 2020:1945832.
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DeMISTifying Paneth Cell Maturation. Cell Mol Gastroenterol Hepatol. 2019; 8(4):643-644.
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Gastroesophageal junction Paneth cell carcinoma with extensive cystic and secretory features - case report and literature review. Diagn Pathol. 2019 Jan 08; 14(1):1.
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Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cell Mol Gastroenterol Hepatol. 2019; 7(3):533-554.
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The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1. Cell Death Differ. 2017 05; 24(5):855-865.