"Keratinocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
| Descriptor ID |
D015603
|
| MeSH Number(s) |
A11.436.397
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Keratinocytes".
Below are MeSH descriptors whose meaning is more specific than "Keratinocytes".
This graph shows the total number of publications written about "Keratinocytes" by people in this website by year, and whether "Keratinocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 2 | 4 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 3 | 4 |
| 2017 | 2 | 3 | 5 |
| 2018 | 3 | 1 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 3 | 5 |
| 2025 | 2 | 2 | 4 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Keratinocytes" by people in Profiles.
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A metabolic alarmin from keratinocytes potentiates systemic humoral immunity. Nature. 2026 04; 652(8108):209-219.
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Therapeutic p63 isoform switching rescues epidermal defects in AEC syndrome. Mol Ther. 2026 Apr 01; 34(4):2324-2342.
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Establishment and characterization of a new immortalized human oral keratinocyte (HOK) cell line harboring various TP53 mutations. Oral Oncol. 2026 Jan; 172:107799.
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Inhibition of formyl peptide receptor-1-mediated cell death as a therapy for lethal cutaneous drug reactions in preclinical models. Nat Commun. 2025 Sep 30; 16(1):8708.
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Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis. Nat Commun. 2025 Apr 01; 16(1):3101.
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Chondroitin sulfate proteoglycan 4 increases invasion of recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma by modifying transforming growth factor-? signalling. Br J Dermatol. 2024 12 23; 192(1):104-117.
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A molecular mechanism for bright color variation in parrots. Science. 2024 11; 386(6721):eadp7710.
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P2X7R-primed keratinocytes are susceptible to apoptosis via GPCR-G??-pERK signal pathways. J Dermatol Sci. 2024 Dec; 116(3):90-99.
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A Mouse Model for Conditional Expression of Activated ?-Catenin in Epidermal Keratinocytes. Transgenic Res. 2024 10; 33(5):513-525.
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Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII?Expression in Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. 2024 Dec; 144(12):2764-2777.e9.