"Leydig Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.
| Descriptor ID |
D007985
|
| MeSH Number(s) |
A05.360.444.849.513 A06.407.312.782.513 A11.382.906 A11.436.513
|
| Concept/Terms |
Leydig Cells- Leydig Cells
- Cells, Leydig
- Testicular Interstitial Cells
- Interstitial Cells, Testicular
- Cell, Testicular Interstitial
- Cells, Testicular Interstitial
- Interstitial Cell, Testicular
- Testicular Interstitial Cell
|
Below are MeSH descriptors whose meaning is more general than "Leydig Cells".
Below are MeSH descriptors whose meaning is more specific than "Leydig Cells".
This graph shows the total number of publications written about "Leydig Cells" by people in this website by year, and whether "Leydig Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 1 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leydig Cells" by people in Profiles.
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Mechanistic screening of reproductive toxicity in a novel 3D testicular co-culture model shows significant impairments following exposure to low-dibutyl phthalate concentrations. Arch Toxicol. 2024 Aug; 98(8):2695-2709.
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Adult Exposure to Di-N-Butyl Phthalate (DBP) Induces Persistent Effects on Testicular Cell Markers and Testosterone Biosynthesis in Mice. Int J Mol Sci. 2022 Aug 05; 23(15).
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The solute carrier family 7 member 11 (SLC7A11) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells. Mol Cell Endocrinol. 2022 06 01; 549:111641.
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Diverse functions of insulin-like 3 peptide. J Endocrinol. 2020 10 01; 247(1):R1-R12.
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GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 06; 16(6):e1008810.
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An approach that someday may boost testosterone biosynthesis in males with late-onset hypogonadism (low testosterone). Proc Natl Acad Sci U S A. 2019 11 12; 116(46):22904-22906.
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Leydig Cell Function in Male Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study. J Clin Oncol. 2019 11 10; 37(32):3018-3031.
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Subcutaneous Leydig Stem Cell Autograft: A Promising Strategy to Increase Serum Testosterone. Stem Cells Transl Med. 2019 01; 8(1):58-65.
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Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells. Biomaterials. 2018 09; 177:125-138.
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Adrenomedullin protects Leydig cells against lipopolysaccharide-induced oxidative stress and inflammatory reaction via MAPK/NF-?B signalling pathways. Sci Rep. 2017 11 28; 7(1):16479.