"Trophoblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA).
Descriptor ID |
D014327
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MeSH Number(s) |
A11.382.992 A16.254.500.766 A16.710.802
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trophoblasts".
Below are MeSH descriptors whose meaning is more specific than "Trophoblasts".
This graph shows the total number of publications written about "Trophoblasts" by people in this website by year, and whether "Trophoblasts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
1998 | 1 | 1 | 2 |
1999 | 3 | 1 | 4 |
2000 | 1 | 1 | 2 |
2001 | 0 | 2 | 2 |
2002 | 1 | 0 | 1 |
2003 | 4 | 1 | 5 |
2004 | 3 | 1 | 4 |
2005 | 1 | 0 | 1 |
2006 | 1 | 1 | 2 |
2007 | 1 | 3 | 4 |
2008 | 1 | 1 | 2 |
2009 | 3 | 2 | 5 |
2010 | 3 | 0 | 3 |
2011 | 2 | 0 | 2 |
2012 | 3 | 0 | 3 |
2013 | 5 | 2 | 7 |
2014 | 2 | 0 | 2 |
2015 | 2 | 2 | 4 |
2016 | 1 | 1 | 2 |
2017 | 1 | 3 | 4 |
2018 | 2 | 0 | 2 |
2019 | 1 | 1 | 2 |
2020 | 5 | 3 | 8 |
2021 | 3 | 0 | 3 |
2022 | 1 | 2 | 3 |
2023 | 0 | 3 | 3 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trophoblasts" by people in Profiles.
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Uncovering Phenotypes in Mutant Mice by Determining Embryo, Organ, Tissue, and Cell Developmental Potential. Cold Spring Harb Protoc. 2024 Jan 02; 2024(1):pdb.over107974.
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Comparison of Four Protocols for In Vitro Differentiation of Human Embryonic Stem Cells into Trophoblast Lineages by BMP4 and Dual Inhibition of Activin/Nodal and FGF2 Signaling. Reprod Sci. 2024 Jan; 31(1):173-189.
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Zika virus co-opts microRNA networks to persist in placental niches detected by spatial transcriptomics. Am J Obstet Gynecol. 2024 Feb; 230(2):251.e1-251.e17.
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First-in-Human, Phase I Dose-Escalation and Dose-Expansion Study of Trophoblast Cell-Surface Antigen 2-Directed Antibody-Drug Conjugate Datopotamab Deruxtecan in Non-Small-Cell Lung Cancer: TROPION-PanTumor01. J Clin Oncol. 2023 10 10; 41(29):4678-4687.
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Circulating trophoblast numbers as a potential marker for pregnancy complications. Prenat Diagn. 2022 08; 42(9):1182-1189.
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A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. Nat Commun. 2022 05 10; 13(1):2548.
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Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens. Cell Stem Cell. 2022 05 05; 29(5):810-825.e8.
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Functional role and regulation of permeability-glycoprotein (P-gp) in the fetal membrane during drug transportation. Am J Reprod Immunol. 2022 02; 87(2):e13515.
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Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice. Stem Cell Res Ther. 2021 08 30; 12(1):487.
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miRNA-149 targets PARP-2 in endometrial epithelial and stromal cells to regulate the trophoblast attachment process. Mol Hum Reprod. 2021 05 29; 27(6).