"CD59 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
| Descriptor ID |
D018957
|
| MeSH Number(s) |
D12.776.395.550.448.140 D12.776.543.484.500.140 D12.776.543.550.418.140
|
| Concept/Terms |
CD59 Antigens- CD59 Antigens
- Antigens, CD59
- Membrane Attack Complex Inhibition Factor
- Protectin
- MACIF
- Membrane Inhibitor of Reactive Lysis
- Homologous Restriction Factor 20
- CD59 Antigen
- HRF20
|
Below are MeSH descriptors whose meaning is more general than "CD59 Antigens".
Below are MeSH descriptors whose meaning is more specific than "CD59 Antigens".
This graph shows the total number of publications written about "CD59 Antigens" by people in this website by year, and whether "CD59 Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "CD59 Antigens" by people in Profiles.
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Overexpression of Human CD55 and CD59 or Treatment with Human CD55 Protects against Renal Ischemia-Reperfusion Injury in Mice. J Immunol. 2017 06 15; 198(12):4837-4845.
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Flow cytometric immunophenotypic analysis of systemic mastocytosis involving bone marrow. Arch Pathol Lab Med. 2014 Sep; 138(9):1210-4.
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Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice. J Neuroinflammation. 2009 Jan 08; 6:2.
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Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats. Haematologica. 2009 Jan; 94(1):29-37.
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Lipid microdomain clustering induces a redistribution of antigen recognition and adhesion molecules on human T lymphocytes. J Immunol. 2002 Mar 15; 168(6):2737-44.
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Detection of "PNH red cell" populations in hematological disorders using the Sephacryl Gel Test micro typing system. Leuk Lymphoma. 1997 Dec; 28(1-2):177-82.