"TATA-Box Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A general transcription factor that plays a major role in the activation of eukaryotic genes transcribed by RNA POLYMERASES. It binds specifically to the TATA BOX promoter element, which lies close to the position of transcription initiation in RNA transcribed by RNA POLYMERASE II. Although considered a principal component of TRANSCRIPTION FACTOR TFIID it also takes part in general transcription factor complexes involved in RNA POLYMERASE I and RNA POLYMERASE III transcription.
| Descriptor ID |
D035181
|
| MeSH Number(s) |
D12.776.260.775.374 D12.776.260.775.875.750.500 D12.776.930.930.374 D12.776.930.930.875.750.500
|
| Concept/Terms |
TATA-Box Binding Protein- TATA-Box Binding Protein
- TATA Box Binding Protein
- Transcription Factor TBP
- TATA-Box-Binding Protein
- RNA Polymerase II TATA-Binding Protein
- RNA Polymerase II TATA Binding Protein
- TATA-Binding Protein
- TATA Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "TATA-Box Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "TATA-Box Binding Protein".
This graph shows the total number of publications written about "TATA-Box Binding Protein" by people in this website by year, and whether "TATA-Box Binding Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2003 | 3 | 1 | 4 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 2 | 4 |
| 2008 | 2 | 1 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "TATA-Box Binding Protein" by people in Profiles.
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Elevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer. Oncotarget. 2017 Jul 25; 8(30):48832-48845.
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MEF2 is an in vivo immune-metabolic switch. Cell. 2013 Oct 10; 155(2):435-47.
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Regulation of the structurally dynamic N-terminal domain of progesterone receptor by protein-induced folding. J Biol Chem. 2013 Oct 18; 288(42):30285-30299.
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Alcohol induces RNA polymerase III-dependent transcription through c-Jun by co-regulating TATA-binding protein (TBP) and Brf1 expression. J Biol Chem. 2011 Jan 28; 286(4):2393-401.
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A hypersensitive estrogen receptor alpha mutation that alters dynamic protein interactions. Breast Cancer Res Treat. 2010 Jul; 122(2):381-93.
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The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12682-7.
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Epidermal growth factor receptor 1 (EGFR1) and its variant EGFRvIII regulate TATA-binding protein expression through distinct pathways. Mol Cell Biol. 2008 Oct; 28(20):6483-95.
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CBF/NF-Y controls endoplasmic reticulum stress induced transcription through recruitment of both ATF6(N) and TBP. J Cell Biochem. 2008 Aug 01; 104(5):1708-23.
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Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation. J Biol Chem. 2008 Jul 11; 283(28):19184-91.
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Instability of expanded CAG/CAA repeats in spinocerebellar ataxia type 17. Eur J Hum Genet. 2008 Feb; 16(2):215-22.