Transcription Factors, TFII
"Transcription Factors, TFII" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.
| Descriptor ID |
D019473
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| MeSH Number(s) |
D12.776.260.775.875 D12.776.930.930.875
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factors, TFII".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors, TFII".
This graph shows the total number of publications written about "Transcription Factors, TFII" by people in this website by year, and whether "Transcription Factors, TFII" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factors, TFII" by people in Profiles.
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The Integrated Genomic Landscape of Thymic Epithelial Tumors. Cancer Cell. 2018 02 12; 33(2):244-258.e10.
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A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. Nat Genet. 2014 Aug; 46(8):844-9.
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Human Mediator enhances basal transcription by facilitating recruitment of transcription factor IIB during preinitiation complex assembly. J Biol Chem. 2006 Jun 02; 281(22):15172-81.
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Definition of a short region of XPG necessary for TFIIH interaction and stable recruitment to sites of UV damage. Mol Cell Biol. 2004 Dec; 24(24):10670-80.
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Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Mol Cell Biol. 2002 Apr; 22(8):2842-52.
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The structural and functional organization of the yeast mediator complex. J Biol Chem. 2001 Nov 09; 276(45):42003-10.
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Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome. Mol Cell Biol. 2001 Apr; 21(7):2281-91.
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Influence of HMG-1 and adenovirus oncoprotein E1A on early stages of transcriptional preinitiation complex assembly. J Biol Chem. 2000 Nov 10; 275(45):35006-12.
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TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair. J Biol Chem. 2000 Feb 11; 275(6):4258-66.
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Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. Genes Dev. 2000 Feb 01; 14(3):349-59.