Transcription Factor TFIIH
"Transcription Factor TFIIH" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A general transcription factor that is involved in basal GENETIC TRANSCRIPTION and NUCLEOTIDE EXCISION REPAIR. It consists of nine subunits including ATP-DEPENDENT DNA HELICASES; CYCLIN H; and XERODERMA PIGMENTOSUM GROUP D PROTEIN.
| Descriptor ID |
D051758
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| MeSH Number(s) |
D12.776.260.775.875.875 D12.776.930.930.875.875
|
| Concept/Terms |
Transcription Factor TFIIH- Transcription Factor TFIIH
- TFIIH, Transcription Factor
- BTF2 Transcription Factor
- Transcription Factor, BTF2
- Transcription Factor BTF2
- BTF2, Transcription Factor
- Transcription Factor IIH
- Basic Transcription Factor 2
- TFIIH Transcription Factor
- Transcription Factor, TFIIH
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor TFIIH".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor TFIIH".
This graph shows the total number of publications written about "Transcription Factor TFIIH" by people in this website by year, and whether "Transcription Factor TFIIH" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factor TFIIH" by people in Profiles.
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Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair. Nat Commun. 2024 Oct 01; 15(1):8511.
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Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases. Nat Commun. 2023 05 13; 14(1):2758.
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A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair. Nucleic Acids Res. 2023 02 22; 51(3):1019-1033.
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Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair. DNA Repair (Amst). 2020 12; 96:102972.
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Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nat Struct Mol Biol. 2019 06; 26(6):397-406.
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Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium. Carcinogenesis. 2016 09; 37(9):888-896.
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Real-time observation of the initiation of RNA polymerase II transcription. Nature. 2015 Sep 10; 525(7568):274-7.
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Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes. J Cell Mol Med. 2013 Dec; 17(12):1598-607.
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Sirt1 suppresses RNA synthesis after UV irradiation in combined xeroderma pigmentosum group D/Cockayne syndrome (XP-D/CS) cells. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):E212-20.
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The anticancer ruthenium complex KP1019 induces DNA damage, leading to cell cycle delay and cell death in Saccharomyces cerevisiae. Mol Pharmacol. 2013 Jan; 83(1):225-34.