Excitatory Amino Acid Transporter 2
"Excitatory Amino Acid Transporter 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glutamate plasma membrane transporter protein found in ASTROCYTES and in the LIVER.
| Descriptor ID |
D027342
|
| MeSH Number(s) |
D12.776.157.530.200.249.500.500.750 D12.776.157.530.450.625.147.750 D12.776.157.530.562.374.781.750 D12.776.157.530.937.250.500.750 D12.776.543.585.200.249.500.500.750 D12.776.543.585.450.625.147.750 D12.776.543.585.562.374.781.750 D12.776.543.585.937.250.500.750
|
| Concept/Terms |
Excitatory Amino Acid Transporter 2- Excitatory Amino Acid Transporter 2
- EAAT2 Neurotransmitter Transporter
- Neurotransmitter Transporter, EAAT2
- EAAT-2 Excitatory Amino Acid Transporter
- EAAT 2 Excitatory Amino Acid Transporter
- GLT-1 Transport Protein
- GLT 1 Transport Protein
- Transport Protein, GLT-1
- SLC1A2 Transporter
- Transporter, SLC1A2
- GluT-1 Glutamate Transporter
- GluT 1 Glutamate Transporter
- Glutamate Transporter, GluT-1
|
Below are MeSH descriptors whose meaning is more general than "Excitatory Amino Acid Transporter 2".
Below are MeSH descriptors whose meaning is more specific than "Excitatory Amino Acid Transporter 2".
This graph shows the total number of publications written about "Excitatory Amino Acid Transporter 2" by people in this website by year, and whether "Excitatory Amino Acid Transporter 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2021 | 0 | 2 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Excitatory Amino Acid Transporter 2" by people in Profiles.
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Toxoplasma gondii infection of neurons alters the production and content of extracellular vesicles directing astrocyte phenotype and contributing to the loss of GLT-1 in the infected brain. PLoS Pathog. 2025 Jun; 21(6):e1012733.
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Olfactory bulb astrocytes mediate sensory circuit processing through Sox9 in the mouse brain. Nat Commun. 2021 09 01; 12(1):5230.
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Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats. Placenta. 2021 09 01; 112:36-44.
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Up-Regulation of the Excitatory Amino Acid Transporters EAAT1 and EAAT2 by Mammalian Target of Rapamycin. Cell Physiol Biochem. 2016; 39(6):2492-2500.
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Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo. J Neurosci. 2016 07 06; 36(27):7079-94.
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Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease. J Exp Med. 2015 Mar 09; 212(3):319-32.
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Pharmacological inhibitions of glutamate transporters EAAT1 and EAAT2 compromise glutamate transport in photoreceptor to ON-bipolar cell synapses. Vision Res. 2014 Oct; 103:49-62.
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Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection. J Clin Invest. 2014 Mar; 124(3):1255-67.
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Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases. Future Med Chem. 2012 Sep; 4(13):1689-700.
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Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011 Oct 01; 21(19):5774-7.