Monomeric GTP-Binding Proteins
"Monomeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of GTPase activators, GDP dissociation inhibitors, and guanine nucleotide exchange factors. This enzyme was formerly listed as EC 3.6.1.47
| Descriptor ID |
D020559
|
| MeSH Number(s) |
D08.811.277.040.330.300.400 D12.644.360.525 D12.776.157.325.515 D12.776.476.525
|
| Concept/Terms |
Monomeric GTP-Binding Proteins- Monomeric GTP-Binding Proteins
- Monomeric GTP Binding Proteins
- Small GTPases
- GTPases, Small
- Monomeric G-Proteins
- Monomeric G Proteins
- Small G-Proteins
- G-Proteins, Small
- Small G Proteins
- G-Proteins, Monomeric
- G Proteins, Monomeric
- GTP-Binding Proteins, Monomeric
- GTP Binding Proteins, Monomeric
ras-Related GTPases- ras-Related GTPases
- GTPases, ras-Related
- ras Related GTPases
- ras-Related GTP-Binding Proteins
- GTP-Binding Proteins, ras-Related
- Proteins, ras-Related GTP-Binding
- ras Related GTP Binding Proteins
- ras-Related G-Proteins
- G-Proteins, ras-Related
- ras Related G Proteins
|
Below are MeSH descriptors whose meaning is more general than "Monomeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Monomeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Monomeric GTP-Binding Proteins" by people in this website by year, and whether "Monomeric GTP-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Monomeric GTP-Binding Proteins" by people in Profiles.
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Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature. 2023 02; 614(7948):572-579.
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Intracellular lipid surveillance by small G protein geranylgeranylation. Nature. 2022 05; 605(7911):736-740.
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BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome. Int J Mol Sci. 2021 Sep 30; 22(19).
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RAB31 marks and controls an ESCRT-independent exosome pathway. Cell Res. 2021 02; 31(2):157-177.
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A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dub? syndrome. Nature. 2020 09; 585(7826):597-602.
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Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain. J Neurosci. 2019 01 16; 39(3):393-411.
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Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is. Genes Dev. 2018 09 01; 32(17-18):1188-1200.
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Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. PLoS One. 2018; 13(7):e0197561.
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Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation. J Nutr. 2018 06 01; 148(6):825-833.
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RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells. Autophagy. 2018; 14(4):637-653.