"ral GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ubiquitously expressed MONOMERIC GTP-BINDING PROTEINS that are involved in intracellular signal transduction. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020725
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.450 D12.644.360.525.450 D12.776.157.325.515.450 D12.776.476.525.450
|
| Concept/Terms |
ral A Protein- ral A Protein
- ral A GTP-Binding Protein
- ral A GTP Binding Protein
- ral GTP-Binding Protein
- GTP-Binding Protein, ral
- ral GTP Binding Protein
- ral Protein
|
Below are MeSH descriptors whose meaning is more general than "ral GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "ral GTP-Binding Proteins".
This graph shows the total number of publications written about "ral GTP-Binding Proteins" by people in this website by year, and whether "ral GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "ral GTP-Binding Proteins" by people in Profiles.
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Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer. Cell Rep. 2021 08 03; 36(5):109491.
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Parallel Rap1>RalGEF>Ral and Ras signals sculpt the C.?elegans nervous system. Dev Biol. 2021 09; 477:37-48.
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Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors. Br J Cancer. 2018 01; 118(1):52-61.
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Two-Step Forward Genetic Screen in Mice Identifies Ral?GTPase-Activating Proteins as Suppressors of Hepatocellular?Carcinoma. Gastroenterology. 2016 08; 151(2):324-337.e12.
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An integrin ?3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat Cell Biol. 2014 May; 16(5):457-68.
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Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion. Mol Cell. 2014 Jan 23; 53(2):209-20.
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Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models. Cancer Biol Ther. 2011 Oct 01; 12(7):598-609.
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The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer Biol Ther. 2010 Nov 15; 10(10):1009-18.
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Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling. Cancer Res. 2010 Jun 01; 70(11):4460-9.
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Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Mol Cancer Res. 2009 Jul; 7(7):1064-77.