"ras Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.
Descriptor ID |
D018631
|
MeSH Number(s) |
D08.811.277.040.330.300.400.500 D12.644.360.525.500 D12.776.157.325.515.500 D12.776.476.525.500
|
Concept/Terms |
ras Proteins- ras Proteins
- ras GTPases
- GTPases, ras
- Gene Products, ras
- ras Gene Products
|
Below are MeSH descriptors whose meaning is more general than "ras Proteins".
Below are MeSH descriptors whose meaning is more specific than "ras Proteins".
This graph shows the total number of publications written about "ras Proteins" by people in this website by year, and whether "ras Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1994 | 1 | 0 | 1 |
1995 | 4 | 1 | 5 |
1996 | 2 | 1 | 3 |
1998 | 1 | 1 | 2 |
1999 | 5 | 2 | 7 |
2000 | 3 | 2 | 5 |
2001 | 4 | 3 | 7 |
2002 | 2 | 4 | 6 |
2003 | 3 | 6 | 9 |
2004 | 3 | 4 | 7 |
2005 | 1 | 10 | 11 |
2006 | 3 | 10 | 13 |
2007 | 6 | 8 | 14 |
2008 | 8 | 9 | 17 |
2009 | 16 | 9 | 25 |
2010 | 6 | 12 | 18 |
2011 | 16 | 18 | 34 |
2012 | 15 | 15 | 30 |
2013 | 18 | 12 | 30 |
2014 | 18 | 14 | 32 |
2015 | 14 | 10 | 24 |
2016 | 6 | 4 | 10 |
2017 | 2 | 9 | 11 |
2018 | 5 | 4 | 9 |
2019 | 5 | 4 | 9 |
2020 | 7 | 3 | 10 |
2021 | 3 | 3 | 6 |
2022 | 1 | 3 | 4 |
2023 | 0 | 1 | 1 |
2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "ras Proteins" by people in Profiles.
-
Early elevations of RAS protein level and activity are critical for the development of PDAC in the context of inflammation. Cancer Lett. 2024 Apr 01; 586:216694.
-
The 8th International RASopathies Symposium: Expanding research and care practice through global collaboration and advocacy. Am J Med Genet A. 2024 Apr; 194(4):e63477.
-
Implications of RAS mutational status in subsets of patients with newly diagnosed acute myeloid leukemia across therapy subtypes. Am J Hematol. 2022 Dec; 97(12):1599-1606.
-
The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery. Am J Med Genet A. 2022 06; 188(6):1915-1927.
-
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia. Signal Transduct Target Ther. 2022 02 21; 7(1):51.
-
Splicing is an alternate oncogenic pathway activation mechanism in glioma. Nat Commun. 2022 01 31; 13(1):588.
-
DIRAS3: An Imprinted Tumor Suppressor Gene that Regulates RAS and PI3K-driven Cancer Growth, Motility, Autophagy, and Tumor Dormancy. Mol Cancer Ther. 2022 01; 21(1):25-37.
-
Inhibition of Elevated Ras-MAPK Signaling Normalizes Enhanced Motor Learning and Excessive Clustered Dendritic Spine Stabilization in the MECP2-Duplication Syndrome Mouse Model of Autism. eNeuro. 2021 Jul-Aug; 8(4).
-
Residue interaction networks of K-Ras protein with water molecules identifies the potential role of switch II and P-loop. Comput Biol Med. 2021 08; 135:104597.
-
Resistance Mutations to BTK Inhibitors Originate From the NF-?B but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway. Front Immunol. 2021; 12:689472.