"ras Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D018631
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.500 D12.644.360.525.500 D12.776.157.325.515.500 D12.776.476.525.500
|
| Concept/Terms |
ras Proteins- ras Proteins
- ras GTPases
- GTPases, ras
- Gene Products, ras
- ras Gene Products
|
Below are MeSH descriptors whose meaning is more general than "ras Proteins".
Below are MeSH descriptors whose meaning is more specific than "ras Proteins".
This graph shows the total number of publications written about "ras Proteins" by people in this website by year, and whether "ras Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 2 | 0 | 2 |
| 2005 | 0 | 4 | 4 |
| 2006 | 1 | 3 | 4 |
| 2007 | 2 | 2 | 4 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 2 | 0 | 2 |
| 2011 | 4 | 3 | 7 |
| 2012 | 4 | 0 | 4 |
| 2013 | 4 | 3 | 7 |
| 2014 | 2 | 4 | 6 |
| 2015 | 2 | 1 | 3 |
| 2016 | 4 | 2 | 6 |
| 2017 | 1 | 2 | 3 |
| 2018 | 3 | 4 | 7 |
| 2019 | 1 | 1 | 2 |
| 2020 | 3 | 4 | 7 |
| 2021 | 3 | 1 | 4 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "ras Proteins" by people in Profiles.
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Update on Pediatric Cancer Surveillance Recommendations for Patients with Neurofibromatosis Type 1, Noonan Syndrome, CBL Syndrome, Costello Syndrome, and Related RASopathies. Clin Cancer Res. 2024 Nov 01; 30(21):4834-4843.
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Germline mutations in a G protein identify signaling cross-talk in T cells. Science. 2024 09 20; 385(6715):eadd8947.
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Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket. Cell. 2024 Oct 31; 187(22):6379-6392.e17.
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The 8th International RASopathies Symposium: Expanding research and care practice through global collaboration and advocacy. Am J Med Genet A. 2024 04; 194(4):e63477.
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Toll-like receptor 2 selectively modulates Ras isoforms expression in Leishmania major infection. Cytokine. 2023 09; 169:156301.
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The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery. Am J Med Genet A. 2022 06; 188(6):1915-1927.
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Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring. J Clin Oncol. 2021 11 20; 39(33):3705-3715.
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Inhibition of Elevated Ras-MAPK Signaling Normalizes Enhanced Motor Learning and Excessive Clustered Dendritic Spine Stabilization in the MECP2-Duplication Syndrome Mouse Model of Autism. eNeuro. 2021 Jul-Aug; 8(4).
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Residue interaction networks of K-Ras protein with water molecules identifies the potential role of switch II and P-loop. Comput Biol Med. 2021 08; 135:104597.
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Parallel Rap1>RalGEF>Ral and Ras signals sculpt the C.?elegans nervous system. Dev Biol. 2021 09; 477:37-48.