Guanine Nucleotide Exchange Factors
"Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.
| Descriptor ID |
D020662
|
| MeSH Number(s) |
D12.644.360.325.300 D12.776.476.325.300
|
| Concept/Terms |
Guanine Nucleotide Exchange Factors- Guanine Nucleotide Exchange Factors
- Guanine-Nucleotide-Releasing Factor
- Guanine Nucleotide Releasing Factor
- GDP Dissociation Factor
- GDP-GTP Exchange Protein
- GDP GTP Exchange Protein
- GDP Dissociation Stimulators
- GDP-GTP Reversing Factors
- Factors, GDP-GTP Reversing
- GDP GTP Reversing Factors
- Reversing Factors, GDP-GTP
- Guanine Nucleotide Releasing Factors
- GDP Exchange Factors
- Exchange Factors, GDP
- Factors, GDP Exchange
- Guanine Nucleotide Exchange Factor
|
Below are MeSH descriptors whose meaning is more general than "Guanine Nucleotide Exchange Factors".
Below are MeSH descriptors whose meaning is more specific than "Guanine Nucleotide Exchange Factors".
This graph shows the total number of publications written about "Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "Guanine Nucleotide Exchange Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 2 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 3 | 6 |
| 2012 | 2 | 1 | 3 |
| 2013 | 3 | 2 | 5 |
| 2014 | 3 | 0 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 2 | 1 | 3 |
| 2021 | 2 | 4 | 6 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanine Nucleotide Exchange Factors" by people in Profiles.
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Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. Nat Commun. 2024 Aug 22; 15(1):7239.
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Tiam1 coordinates synaptic structural and functional plasticity underpinning the pathophysiology of neuropathic pain. Neuron. 2023 07 05; 111(13):2038-2050.e6.
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Loss-of-function variants in MYCBP2 cause neurobehavioural phenotypes and corpus callosum defects. Brain. 2023 04 19; 146(4):1373-1387.
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Translational relevance of SOS1 targeting for KRAS-mutant colorectal cancer. Mol Carcinog. 2023 07; 62(7):1025-1037.
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Recurrent Breast Abscesses in a Female with Autosomal Dominant Hyper-IgE Syndrome. J Clin Immunol. 2022 05; 42(4):889-891.
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RCC1 Expression as a Prognostic Marker in Colorectal Liver Oligometastases. Pathol Oncol Res. 2021; 27:1610077.
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Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021 11; 53(11):1543-1552.
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A Multi-center Genome-wide Association Study of Cervical Dystonia. Mov Disord. 2021 12; 36(12):2795-2801.
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Haploinsufficiency of ARFGEF1 is associated with developmental delay, intellectual disability, and epilepsy with variable expressivity. Genet Med. 2021 10; 23(10):1901-1911.
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Parallel Rap1>RalGEF>Ral and Ras signals sculpt the C.?elegans nervous system. Dev Biol. 2021 09; 477:37-48.