Eukaryotic Initiation Factor-2B
"Eukaryotic Initiation Factor-2B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A guanine nucleotide exchange factor that acts to restore EUKARYOTIC INITIATION FACTOR-2 to its GTP bound form.
| Descriptor ID |
D020717
|
| MeSH Number(s) |
D12.644.360.325.300.050 D12.776.476.325.300.050 D12.776.835.725.868.374
|
| Concept/Terms |
Eukaryotic Initiation Factor-2B- Eukaryotic Initiation Factor-2B
- Eukaryotic Initiation Factor 2B
- Peptide Initiation Factor EIF-2B
- Peptide Initiation Factor EIF 2B
- EIF2B1
- Eukaryotic Peptide Initiation Factor-2B
- Eukaryotic Peptide Initiation Factor 2B
- EIF-2B
- EIF 2B
- EIF2B
|
Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-2B".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-2B".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-2B" by people in this website by year, and whether "Eukaryotic Initiation Factor-2B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-2B" by people in Profiles.
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Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation. PLoS Biol. 2017 Sep; 15(9):e2002623.
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Imexon induces an oxidative endoplasmic reticulum stress response in pancreatic cancer cells. Mol Cancer Res. 2012 Mar; 10(3):392-400.
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PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cells. J Biol Chem. 2008 Dec 19; 283(51):35474-85.
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Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits. J Biol Chem. 2004 Aug 27; 279(35):37087-94.
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Translational control of protein synthesis in muscle and liver of growth hormone-treated pigs. Endocrinology. 2003 Apr; 144(4):1273-83.
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Developmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs. Am J Physiol Endocrinol Metab. 2000 Dec; 279(6):E1226-34.